Prediction for Bronchopulmonary Dysplasia
Development of a Nomogram for Predicting Bronchopulmonary Dysplasia in Infants
1 other identifier
observational
5,000
1 country
1
Brief Summary
In this Multi-center study performed from January 2018, we reviewed data on infants whose gestational ages were below 36 weeks. we collected data containing maternal diseases and neonatal clinical features. LASSO regression was used to select variables for the risk model. Then, we used multivariable logistic regression to build the prediction model incorporating these selected features. Discrimination was assessed by the C-index, and and calibration of the model was assessed by and calibration curve and the Hosmer-Lemeshow test.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2018
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2018
CompletedFirst Submitted
Initial submission to the registry
December 18, 2021
CompletedFirst Posted
Study publicly available on registry
January 6, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2022
CompletedJanuary 6, 2022
December 1, 2021
4.9 years
December 18, 2021
December 18, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
bronchopulmonary dysplasia occurs
Number of cases of bronchopulmonary dysplasia
2 weeks after admission
Study Arms (2)
bronchopulmonary dysplasia group
infants diagnosed with bronchopulmonary dysplasia
no bronchopulmonary dysplasia
infants not diagnosed with bronchopulmonary dysplasia
Interventions
We observe the incidence of bronchopulmonary dysplasia
Eligibility Criteria
Patients were recruited from Multi-center Collaborative Group Hospital Neonatal Intensive Care Unit (NICU) Department. The data was collected from medical records. Patients with GAs \<36 weeks, and who were admitted to the NICU within 24 h after birth were included, and the length of stay was more than 1 week.patients with inherited disease, metabolic disorders and multiple malformations were excluded.
You may qualify if:
- Patients were recruited from Multi-center Collaborative Group Hospital Neonatal Intensive Care Unit (NICU) Department.
- Patients with gestational age \<36 weeks
- admitted to the NICU within 24 h after birth
- the length of stay was more than 1 week
You may not qualify if:
- patients with inherited disease, metabolic disorders and multiple malformations.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Kai Mulead
Study Sites (1)
Qianfoshan Hospital
Jinan, Shandong, 251400, China
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
MU Kai, Doctor
Qianfoshan Hospital
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- professor
Study Record Dates
First Submitted
December 18, 2021
First Posted
January 6, 2022
Study Start
January 1, 2018
Primary Completion
December 1, 2022
Study Completion
December 1, 2022
Last Updated
January 6, 2022
Record last verified: 2021-12
Data Sharing
- IPD Sharing
- Will not share