Asthma During Pregnancy; Impact of Severity

NCT05180877 | Completed DMC

• 1 other identifier: Soh-Med-21-09-35
• Study Type: observational
• Target: 137
• Locations: 1 country
• Sites: 1

Brief Summary

bronchial asthma (BA) may affect pregnancy and this affection may increase with increasing asthma severity. This study was designed to detect the effect of asthma severity on the course of asthma during pregnancy and its effect on the pregnancy and perinatal outcome

Conditions

Bronchial Asthma

Keywords

Bronchial asthma; Asthma; pregnancy; Asthma severity

Outcome Measures

Primary Outcomes (2)

• maternal complications

  Occurrence any pregnancy related complication to the parturient women was recorded in both study groups.

  from the start of inclusion to the study till termination of pregnancy, average 9 months period

• perinatal complications

  Incidence of any fetal or neonatal complication was recorded

  from the start of inclusion to the study till termination of pregnancy, average 9 months period

Study Arms (2)

Intermittent& mild persistent asthma

According to asthma severity assessment, this group included asthmatic pregnant females patients with intermittent asthma and mild persistent asthma

Moderate& severe persistent asthma

According to asthma severity assessment, this group included asthmatic pregnant females patients with Moderate\& severe persistent asthma

Eligibility Criteria

• Age: 18 Years+
• Gender Eligibility Details: pregnant asthmatic women
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Pregnant asthmatic female patients presenting in first trimester to inpatient or outpatients clinic of chest department.

You may qualify if:

• pregnant women in ages 18y or more with confirmed diagnosis of bronchial asthma presenting in1st trimester to inpatient or outpatients clinic of chest department.

You may not qualify if:

• Patients with Chest diseases other than bronchial asthma and patients with cardiac disease.

Sponsors & Collaborators

• Sohag University: lead

Study Sites (1)

Sohag University

Sohag, 82425, Egypt

Location

Related Publications (3)

• Dharmage SC, Perret JL, Custovic A. Epidemiology of Asthma in Children and Adults. Front Pediatr. 2019 Jun 18;7:246. doi: 10.3389/fped.2019.00246. eCollection 2019.

  PMID: 31275909 BACKGROUND

• Robijn AL, Murphy VE, Gibson PG. Recent developments in asthma in pregnancy. Curr Opin Pulm Med. 2019 Jan;25(1):11-17. doi: 10.1097/MCP.0000000000000538.

  PMID: 30407268 BACKGROUND

• National Asthma Education and Prevention Program. Expert Panel Report 3 (EPR-3): Guidelines for the Diagnosis and Management of Asthma-Summary Report 2007. J Allergy Clin Immunol. 2007 Nov;120(5 Suppl):S94-138. doi: 10.1016/j.jaci.2007.09.043.

  PMID: 17983880 BACKGROUND

MeSH Terms

Conditions

Asthma

Condition Hierarchy (Ancestors)

Bronchial Diseases; Respiratory Tract Diseases; Lung Diseases, Obstructive; Lung Diseases; Respiratory Hypersensitivity; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assistant professor

Study Record Dates

• First Submitted: November 20, 2021
• First Posted: January 6, 2022
• Study Start: April 1, 2019
• Primary Completion: May 31, 2020
• Study Completion: June 30, 2020
• Last Updated: January 6, 2022

Record last verified: 2021-12

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)