NCT05175911

Brief Summary

Effective initial stabilization of preterm neonates in the initial 60 minutes of life ("golden hour") was shown to improve outcomes. Keys components include anticipative and collaborative approach, respiratory support, thermal regulation and early initiation of parenteral nutrition. The objective is to complete the admission within 60 minutes of delivery.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jan 2022

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 1, 2021

Completed
1 month until next milestone

First Posted

Study publicly available on registry

January 4, 2022

Completed
6 days until next milestone

Study Start

First participant enrolled

January 10, 2022

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2023

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2023

Completed
Last Updated

March 9, 2022

Status Verified

March 1, 2022

Enrollment Period

1.1 years

First QC Date

December 1, 2021

Last Update Submit

March 7, 2022

Conditions

Keywords

premature birthgolden hour60 minutes

Outcome Measures

Primary Outcomes (4)

  • Completion of the procedure : closing time of the incubator

    Number of minutes of life at incubator closure

    1 hour

  • Glycemia at admission and within 24 hours

    blood glucose measurement on admission and then every 3 hours for the first 24 hours of life

    24 hours

  • Thermal stability : temperature at admission and at the end of the procedure

    1 hour

  • Mortality rate

    3 months

Secondary Outcomes (9)

  • Process of the procedure:

    1 hour

  • Incidence of hypotension and bradycardia

    1 hour

  • Intubation rate and duration of mechanical ventilation

    3 months

  • Need for surfactant administration and time of administration

    3 days

  • Comorbidities of prematurity: NEC, BPD, ROP, sepsis, PDA, cPVL, IVH

    3 months

  • +4 more secondary outcomes

Study Arms (1)

premature infants

premature infants less than 31 weeks of gestation or weighting less than 1300 g

Other: golden hour : an initial standardized stabilization

Interventions

This is a quality improvement project to evaluate the implementation of "Golden hour", a standardized stabilization during the first hour of life in inborn preterm infants younger than 31 weeks of gestational age or weighting less than 1300 g in the NICU of the University of Liege. There is no comparative arm.

premature infants

Eligibility Criteria

AgeUp to 1 Hour
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

Premature younger than 31 weeks of gestational age or less than 1300 g expected

You may qualify if:

  • Premature infants (\< 31 weeks' gestation)
  • Infants with expected weight less than 1300 g
  • Inborn babies

You may not qualify if:

  • Infants outborn
  • Infants with major congenital anomalies (laparoschisis, omphalocèle, diaphragmatic hernia, …)
  • Parental refusal

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHU Liège

Liège, 4000, Belgium

RECRUITING

MeSH Terms

Conditions

Premature Birth

Condition Hierarchy (Ancestors)

Obstetric Labor, PrematureObstetric Labor ComplicationsPregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital Diseases

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
3 Months
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Doctor

Study Record Dates

First Submitted

December 1, 2021

First Posted

January 4, 2022

Study Start

January 10, 2022

Primary Completion

March 1, 2023

Study Completion

June 1, 2023

Last Updated

March 9, 2022

Record last verified: 2022-03

Data Sharing

IPD Sharing
Will not share

Locations