Transthoracic Ultrasonography Findings and Their Relation to Spirometric Indices in Patients With Obstructive and Restrictive Respiratory Diseases

NCT05175313 | Unknown

• 1 other identifier: Soh-Med-21-12-15
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Evaluation of respiratory function is considered a crucial component in the assessment of patients with a wide range of respiratory diseases. Spirometry is considered a common method of measuring pulmonary function. Recently, Transthoracic ultrasound yields important diagnostic information within minutes. Respiratory muscle ultrasound is used to evaluate the anatomy and function of the respiratory system.

Conditions

Lung Ultrasound; Spirometry; Respiratory Diseases; Diaphragm Ultrasound

Outcome Measures

Primary Outcomes (1)

• investigate the correlation between transthoracic ultrasonography findings and their relation to spirometric indices in patients with different respiratory diseases.

  we will study the degree of change in lung ultrasound, diaphragm, and respiratory muscles ultrasound, inferior vena cava ultrasound in obstructive and restrictive respiratory diseases .also, we find their correlation with spirometric indices in these diseases.

  6months

Study Arms (3)

normal people

people who don't complain of respiratory diseases will be examined by chest ultrasound and pulmonary function test.

Radiation: transthoracic ultrasonography; Device: spirometry

obstructive respiratory diseases

the patients who are diagnosed with either COPD or asthma.

Radiation: transthoracic ultrasonography; Device: spirometry

restrictive respiratory diseases

patient with either ILD

Radiation: transthoracic ultrasonography; Device: spirometry

Interventions

transthoracic ultrasonography RADIATION

1. lung ultrasonography 2. Diaphragm and respiratory muscle ultrasound 3. inferior vena cava ultrasound

normal people; obstructive respiratory diseases; restrictive respiratory diseases

spirometry DEVICE

pulmonary function test : FVC, FEV1, FEV1/FVC will be measured.

normal people; obstructive respiratory diseases; restrictive respiratory diseases

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

COPD: include patients with chronic bronchitis and emphysema. asthma: patients with paroxysmal attacks of chest tightness .wheezes and cough. ILD(interstitial lung diseases )

You may qualify if:

• age \>18 years 2-patients diagnosed with COPD or asthma. 3-patients diagnosed with ILD or any other restrictive lung diseases. 4-normal people.

You may not qualify if:

• age \<18 years old.
• critically ill patients in intensive care units.
• patients with neurological diseases.

Sponsors & Collaborators

• Sohag University: lead
• Cairo University: collaborator

Study Sites (1)

Sohag university hospital

Sohag, Egypt

RECRUITING

Related Publications (5)

• Santana PV, Cardenas LZ, Albuquerque ALP, Carvalho CRR, Caruso P. Diaphragmatic ultrasound: a review of its methodological aspects and clinical uses. J Bras Pneumol. 2020 Nov 20;46(6):e20200064. doi: 10.36416/1806-3756/e20200064. eCollection 2020.

  PMID: 33237154 BACKGROUND

• Smargiassi A, Inchingolo R, Tagliaboschi L, Di Marco Berardino A, Valente S, Corbo GM. Ultrasonographic assessment of the diaphragm in chronic obstructive pulmonary disease patients: relationships with pulmonary function and the influence of body composition - a pilot study. Respiration. 2014;87(5):364-71. doi: 10.1159/000358564. Epub 2014 Apr 11.

  PMID: 24732295 BACKGROUND

• O'Hara DN, Pavlov A, Taub E, Ahmad S. Ultrasonographic modeling of diaphragm function: A novel approach to respiratory assessment. PLoS One. 2020 Mar 12;15(3):e0229972. doi: 10.1371/journal.pone.0229972. eCollection 2020.

  PMID: 32163474 BACKGROUND

• Santana PV, Cardenas LZ, de Albuquerque ALP, de Carvalho CRR, Caruso P. Diaphragmatic ultrasound findings correlate with dyspnea, exercise tolerance, health-related quality of life and lung function in patients with fibrotic interstitial lung disease. BMC Pulm Med. 2019 Oct 21;19(1):183. doi: 10.1186/s12890-019-0936-1.

  PMID: 31638951 BACKGROUND

• Zanforlin A, Giannuzzi R, Nardini S, Testa A, Soldati G, Copetti R, Marchetti G, Valente S, Inchingolo R, Smargiassi A. The role of chest ultrasonography in the management of respiratory diseases: document I. Multidiscip Respir Med. 2013 Aug 9;8(1):54. doi: 10.1186/2049-6958-8-54.

  PMID: 23937880 BACKGROUND

MeSH Terms

Conditions

Respiratory Tract Diseases

Interventions

Spirometry

Intervention Hierarchy (Ancestors)

Respiratory Function Tests; Diagnostic Techniques, Respiratory System; Diagnostic Techniques and Procedures; Diagnosis

Central Study Contacts

esraa F Abdelaal, assistant lecturer

CONTACT

01090490019; esraa.faragallah@.med.sohag.edu.eg

Kamal A Atta, professor

CONTACT

01090410500

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assistant lecturer

Study Record Dates

• First Submitted: December 14, 2021
• First Posted: January 3, 2022
• Study Start: January 1, 2023
• Primary Completion: June 1, 2023
• Study Completion: June 1, 2023
• Last Updated: April 12, 2023

Record last verified: 2023-04

Locations

EG (1)