Breaking of Sitting Time Prevents Lower Leg Swelling

NCT05173558 | Completed

• 1 other identifier: Break_Sitt
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

Sitting or standing during a prolonged and uninterrupted period of time is related to negative health outcomes, such as lower extremity swelling. It is unknown if interrupting sedentary behavior by including brief bouts of standing up to the sitting time can attenuate lower leg swelling. Thus, our purpose is to examine if breaking sitting time by adding sit-to-stand transitions attenuates or even prevents lower leg swelling, compared with uninterrupted motionless standing and uninterrupted motionless sitting, using localized bioelectrical impedance raw parameters.

Conditions

Edema Leg

Keywords

Bioimpedance; Raw BIA parameters; Extracellular water expansion; Sedentary behaviour

Outcome Measures

Primary Outcomes (4)

• Phase Angle (º)

  The bioimpedance AKERN BIA 101/BIVA PRO was used to assess physical parameters. Akern is a phase-sensitive device that measures phase angle (PhA).

  8 weeks

• Impedance (Ohm)

  The bioimpedance AKERN BIA 101/BIVA PRO was used to assess physical parameters. Akern is a phase-sensitive device that measures impedance (Z).

  8 weeks

• Resistance (Ohm)

  The bioimpedance AKERN BIA 101/BIVA PRO was used to assess physical parameters. Akern is a phase-sensitive device that measures phase angle (PhA) and impedance (Z), and then calculates resistance (R).

  8 weeks

• Reactance (Ohm)

  The bioimpedance AKERN BIA 101/BIVA PRO was used to assess physical parameters. Akern is a phase-sensitive device that measures phase angle (PhA) and impedance (Z), and then calculates reactance (Xc).

  8 weeks

Secondary Outcomes (6)

• Fat Free Mass (kg)

  8 weeks

• Fat mass (kg)

  8 weeks

• Weight (kg)

  8 weeks

• Height (cm)

  8 weeks

• Blood pressure (mmHg)

  8 weeks

Study Arms (3)

Uninterrupted motionless standing

EXPERIMENTAL

20minutes of uninterrupted motionless standing

Behavioral: Uninterrupted motionless standing

Uninterrupted motionless sitting

EXPERIMENTAL

20 minutes of uninterrupted motionless sitting

Behavioral: Uninterrupted motionless sitting

Sit-to-stand transitions

EXPERIMENTAL

20 minutes of sit-to-stand transitions (1 minute sitting with 1 minute standing)

Behavioral: Sit-to-stand transitions

Interventions

Uninterrupted motionless standing BEHAVIORAL

Participants remained 20 minutes of uninterrupted motionless standing

Uninterrupted motionless standing

Uninterrupted motionless sitting BEHAVIORAL

Participants remained 20 minutes of uninterrupted motionless sitting

Uninterrupted motionless sitting

Sit-to-stand transitions BEHAVIORAL

20 minutes of sit-to-stand transitions (1 minute sitting with 1 minute standing)

Sit-to-stand transitions

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• BMI ranging between 18.5 to 29.9 kg/m2;
• Not taking any medications at the time of the measurements;
• All women should have a (self-reported) regular menstrual cycle.

You may not qualify if:

• Self-reported inability to stand for 20min without moving the lower limbs
• An active smoking status
• Presence of diabetes

Sponsors & Collaborators

• Faculdade de Motricidade Humana: lead

Study Sites (1)

Faculdade de Motricidade Humana

Oeiras, Cruz-Quebrada, 1409-002, Portugal

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: November 30, 2021
• First Posted: December 30, 2021
• Study Start: March 1, 2020
• Primary Completion: June 30, 2020
• Study Completion: July 31, 2020
• Last Updated: January 18, 2022

Record last verified: 2022-01

Data Sharing

• IPD Sharing: Will not share

Locations

PT (1)