Investigating Immune Escape by SARS-CoV-2 Variants
1 other identifier
observational
38
1 country
1
Brief Summary
The purpose of this protocol is to investigate the ability of pre-existing immunity by natural infection or vaccination to prevent infections by emerging SARS-CoV-2 variants.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started May 2021
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 29, 2021
CompletedFirst Submitted
Initial submission to the registry
December 16, 2021
CompletedFirst Posted
Study publicly available on registry
December 29, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
October 15, 2023
CompletedNovember 8, 2023
November 1, 2023
1.6 years
December 16, 2021
November 6, 2023
Conditions
Outcome Measures
Primary Outcomes (1)
Assessing immunity
Assess immune escape among people with vaccination or natural immunity
1 year
Interventions
No intervention, prospective, cohort study.
Eligibility Criteria
Adults living in Los Angeles County
You may qualify if:
- People who have been fully vaccinated for COVID-19 2-12 weeks prior to enrollment or individuals \<3 months post-COVID-19 infection.
- Collection of samples for blood samples will be done only from healthy, nonpregnant adults who weigh at least 110 pounds.
- Participants must be able to provide informed consent.
You may not qualify if:
- Subjects considered vulnerable including children, pregnant women, nursing home residents, or other institutionalized persons, fetuses, prisoners, and persons without decisional capacity.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University of California, Los Angeleslead
- Advarracollaborator
Study Sites (1)
Curative
San Dimas, California, 91773, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
December 16, 2021
First Posted
December 29, 2021
Study Start
May 29, 2021
Primary Completion
December 31, 2022
Study Completion
October 15, 2023
Last Updated
November 8, 2023
Record last verified: 2023-11
Data Sharing
- IPD Sharing
- Will not share
This will not be available.