NCT05168553

Brief Summary

Retraetment of failed previous endodontic treated mature permenant teeth with revascularization versus retreatment by conventional endodontic treatment

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Dec 2021

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 12, 2021

Completed
Same day until next milestone

Study Start

First participant enrolled

December 12, 2021

Completed
11 days until next milestone

First Posted

Study publicly available on registry

December 23, 2021

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 11, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 11, 2022

Completed
Last Updated

December 23, 2021

Status Verified

December 1, 2021

Enrollment Period

12 months

First QC Date

December 12, 2021

Last Update Submit

December 22, 2021

Conditions

Revascularization

Outcome Measures

Primary Outcomes (2)

  • Clinical success

    Number of participants with pain, mobility and/or fistulous tract (+/-)

    1 year

  • Radiographic success

    Absence of periapical radiolucency

    1 year

Study Arms (2)

Revasularization

EXPERIMENTAL
Other: Revascualrization

Conventional endodontic treatment

ACTIVE COMPARATOR
Other: Conventional endodontic treatment

Interventions

RevascualrizationOTHER

Regain pulp vascularity for mature permenant teeth

Revasularization
Conventional endodontic treatmentOTHER

Root canal treatment of permenant mature teeth with mechanical preparation and cleaning followed by canal obturation by inert material ( gutta percha)

Conventional endodontic treatment

Eligibility Criteria

Age10 Years - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Pescence of failed endodontic treated mature permenant tooth
  • Healthy patients
  • Age of 10 years to 18 years

You may not qualify if:

  • Medically compromised patients
  • Mentally compromised patients

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Clinical professor

Study Record Dates

First Submitted

December 12, 2021

First Posted

December 23, 2021

Study Start

December 12, 2021

Primary Completion

December 11, 2022

Study Completion

December 11, 2022

Last Updated

December 23, 2021

Record last verified: 2021-12