Effectiveness of the Decolonization Circuit of S. Aureus, Reducing Infection in Primary Arthroplasty of the Lower Limb

NCT05158322 | Completed

• 1 other identifier: DESCO-2021
• Study Type: observational
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

Lower limb joint replacement surgery is one of the most prevalent globally. In our center, more than 400 lower limb arthroplasties (LLA) are performed annually. Developing a Surgical Site Infection (SSI) after (LLA) increases morbidity, mortality and healthcare costs. Staphylococcus aureus is the main causative agent of SSI and especially in LLA. One third of the population is a nasal carrier of Staphylococcus aureus, being a risk factor for patients who have to undergo knee replacement or hip replacement. Several studies have confirmed that the detection of S. aureus carriers and their subsequent decolonization reduces SSI rates

Conditions

Nurse's Role; Surgical Site Infection; Patient Satisfaction

Keywords

Decolonization S. Aureus

Outcome Measures

Primary Outcomes (1)

• Evaluate with a VAS scale (0-10) the satisfaction of the participant with the information on the decolonization process of S. aureus.

  The participant is satisfied with the information received throughout the decolonization. to be assessed with the EVA scale (0 not at all satisfied / 10 very satisfied)

  6 weeks

Secondary Outcomes (1)

• The participant evaluates his social well-being on the VAS scale (0-10) based on the care received by professionals throughout the S. aureus decolonization process. The number of patients who scored 9 or 10 on the VAS scale will be assessed as satisfied.

  6 weeks

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All the patients who are going to be operated

You may qualify if:

• Over 18 years old
• Patients who are going to undergo knee or hip replacement surgery.
• Patients with a positive result in the first nasal smear to S. aureus, and follow the decolonization protocol.
• Patients who give their informed consent to participate in the study.

You may not qualify if:

• Patients scheduled for VPE less than 2 days after surgery.
• Patients unable to give their informed consent freely. Inadequate cognitive ability

Sponsors & Collaborators

• Corporacion Parc Tauli: lead

Study Sites (1)

Corporació Sanitària Parc Taulí

Sabadell, Barcelona, 08208, Spain

Location

MeSH Terms

Conditions

Surgical Wound Infection; Patient Satisfaction

Condition Hierarchy (Ancestors)

Wound Infection; Infections; Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Treatment Adherence and Compliance; Health Behavior; Behavior

Study Officials

• Francisco Zamora-Carmona, Nurse

  Corporació Parc Tauli

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Target Duration: 6 Weeks
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Enfermero Práctica Avanzada

Study Record Dates

• First Submitted: November 25, 2021
• First Posted: December 15, 2021
• Study Start: October 14, 2021
• Primary Completion: March 16, 2026
• Study Completion: March 16, 2026
• Last Updated: March 20, 2026

Record last verified: 2026-03

Locations

ES (1)