NCT05154071

Brief Summary

Current evidence suggest that regrouping patient supported by veno-venous ECMO in high-volume centre could improve outcome. A dedicated ECMO unit was implemented in Dijon. The objective of the present study was to evaluate the implementation of this unit. The hypothesis was that patient taken care within this structured care system would have lower mortality. This research comprises a retrospective observational study conducted in Dijon university hospital

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
172

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Oct 2021

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2021

Completed
20 days until next milestone

First Submitted

Initial submission to the registry

October 21, 2021

Completed
11 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2021

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2021

Completed
9 days until next milestone

First Posted

Study publicly available on registry

December 10, 2021

Completed
Last Updated

January 29, 2026

Status Verified

January 1, 2026

Enrollment Period

1 month

First QC Date

October 21, 2021

Last Update Submit

January 28, 2026

Conditions

Extracorporeal Membrane Oxygenation

Outcome Measures

Primary Outcomes (1)

  • Mortality rate

    90 days

Secondary Outcomes (3)

  • Rate of ECMO adverse events

    through study completion, an average of 3 years

  • Hospital length of stay

    through study completion, an average of 3 years

  • ICU length of stay

    through study completion, an average of 3 years

Study Arms (2)

ECMO VV dedicated unit

Patient having benefited from an ECMO within the structured care unit

Other: Collection of medical data

ECMO VV without dedicated unit

Patient having benefited from an ECMO without the structured care unit

Other: Collection of medical data

Interventions

Collection of medical dataOTHER

Collection of adverse events, of mortality, length of hospitalization

ECMO VV dedicated unitECMO VV without dedicated unit

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients supported by veno-venous ECMO

You may qualify if:

  • patient in an adult Dijon ICUs supported by veno-venous ECMO
  • patient hospitalized between January the 1st 2011 and June the 30th 2021

You may not qualify if:

  • Refusal to participate,
  • patient admitted to pediatric ICU

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Chu Dijon Bourogne

Dijon, 21000, France

Location

Related Publications (1)

  • Nguyen M, Kabbout V, Berthoud V, Gounot I, Dransart-Raye O, Douguet C, Bouchot O, Morgant MC, Bouhemad B, Guinot PG. Implementation of a regional multidisciplinary veno-venous extracorporeal membrane oxygenation unit improved survival: a historical cohort study. Can J Anaesth. 2022 Jul;69(7):859-867. doi: 10.1007/s12630-022-02259-4. Epub 2022 May 2.

    PMID: 35501590RESULT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 21, 2021

First Posted

December 10, 2021

Study Start

October 1, 2021

Primary Completion

November 1, 2021

Study Completion

December 1, 2021

Last Updated

January 29, 2026

Record last verified: 2026-01

Locations

FR(1)