Forceps Biopsy Versus Cryo-biopsy in the Diagnosis of Lung Cancer

NCT05151419 | Completed

• 1 other identifier: 21/7/2020
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

This study was comprised of 30 patients who were scheduled for a diagnostic bronchoscopy due to a suspicion of lung cancer in order to obtain tissue samples for a final diagnosis , four biopsies were taken by each of cryobiopsy and forceps biopsy , to evaluate and compare the diagnostic yield of endobronchial cryobiopsy and forceps biopsy in the diagnosis of lung cancer .

Conditions

Lung Cancer

Keywords

bronchoscope, cryo-biopsy

Outcome Measures

Primary Outcomes (1)

• Comparative study between Endobronchial Forceps-Biopsy and Cryo-Biopsy in the Diagnosis of bronchogenic carcinoma

  The comparison between groups regarding qualitative data was done by using Chi-square test and/or Fisher exact test when the expected count in any cell found less than 5.at week 40

  comprative , week 40

Study Arms (1)

bronchoscope ,forceps,cryo-biopsy

OTHER

biopies were taken from the lung mass using forceps and cryo-biopsy to evalute diagnostic yield of cryo-biosy versus forceps in the diagnosis of lung cancer

Procedure: bronchoscpe

Interventions

bronchoscpe PROCEDURE

bronchoscopic biopsy from lung mass using cryobiopsy and forceps

Also known as: bronchoscope

bronchoscope ,forceps,cryo-biopsy

Eligibility Criteria

• Age: 47 Years - 88 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• severe uncorrected hypoxemia despite supplemental oxygen treatment
• unstable angina
• uncontrolled arrhythmias,
• severe hypercarbia,
• unstable cervical spine.
• Coagulopathy that cannot be reversed
• Chronic obstructive pulmonary disease (COPD) exacerbation
• Severe Illness
• old age
• malnutrition
• Patient who refused to have a bronchoscopy performed

You may not qualify if:

• Patients' histories, including age, sex, and smoking status, were documented for all participants in the trial Clinical examination and medical history Complete blood count, serum creatinine, liver enzymes, INR, bleeding time, and clotting time are all routine laboratory tests Plain chest X-ray and chest computed tomography were used in the radiological workup\* Arterial blood gas on room air. bronchoscopy and biopsy taking with forceps and cryobiopsy

Sponsors & Collaborators

• Nashwa Ahmed Mohammad amin: lead

Study Sites (1)

Benha University Hospital- Chest Department

Cairo, Egypt

Location

MeSH Terms

Conditions

Lung Neoplasms

Interventions

Bronchoscopes

Condition Hierarchy (Ancestors)

Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lung Diseases; Respiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Endoscopes; Diagnostic Equipment; Equipment and Supplies; Surgical Equipment

Study Officials

• nashwa ah amin, MD

  nashwa ahmed amin

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Nashwa Ahmed Mohammad amin

Model Details: A total number of 30 participants were enrolled in our study. These individuals had a diagnostic bronchoscopy because they had a suspicion of lung cancer and needed tissue samples to confirm the diagnosis. All of the procedures were carried out with 2% lidocaine instillation and midazolam IV sedation

Study Record Dates

• First Submitted: November 14, 2021
• First Posted: December 9, 2021
• Study Start: July 21, 2020
• Primary Completion: June 5, 2021
• Study Completion: September 16, 2021
• Last Updated: December 9, 2021

Record last verified: 2021-11

Locations

EG (1)