SARS CoV-2 Infection and Inflammatory Biomarkers

NCT05145751 | Completed

• 1 other identifier: 46937
• Study Type: observational
• Target: 115
• Locations: 1 country
• Sites: 1

Brief Summary

Early research suggests that inflammation plays a key role in the development of SARS CoV-2 infection. The immune response to respiratory infection is characterized by an influx of neutrophils to the lungs. This study ought to investigate the association of simple biomarkers such as NLR and PLR with the clinical outcome in SARS CoV-2 infection patients.

Conditions

COVID-19; Inflammation

Keywords

COVID-19; Biomarkers; Inflammation

Outcome Measures

Primary Outcomes (1)

• Outcome

  Outcome after COVID-19 infection

  1 year

Study Arms (1)

COVID-19 infection

Consecutive patients with polymerase chain reaction (PCR) confirmed SARS CoV-2 infection

Other: Simple inflammatory biomarkers measurement

Interventions

Simple inflammatory biomarkers measurement OTHER

In patients with polymerase chain reaction (PCR) confirmed SARS CoV-2 infection the values of simple inflammatory biomarkers such NLR will be measured

Also known as: Consecutive patients with polymerase chain reaction (PCR) confirmed SARS CoV-2 infection

COVID-19 infection

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Consecutive patients with SARS CoV-2 infection who were treated by the Department of Respiratory Medicine in the UHL will be done. The subjects will be followed from admission to the hospital and up until discharge, transfer to the ICU or death

You may qualify if:

• Consecutive patients with polymerase chain reaction (PCR) confirmed SARS CoV-2 infection

You may not qualify if:

• Patients aged\<18 years

Sponsors & Collaborators

• University of Thessaly: lead

Study Sites (1)

Univeristy of Thessaly

Larissa, Thessaly, 41110, Greece

Location

MeSH Terms

Conditions

COVID-19; Inflammation

Interventions

Polymerase Chain Reaction

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Nucleic Acid Amplification Techniques; Genetic Techniques; Investigative Techniques

Study Officials

• Eleni Arnaoutoglou, M.D., Ph.D.

  Study Chair

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor of Anesthesiology

Study Record Dates

• First Submitted: December 2, 2021
• First Posted: December 6, 2021
• Study Start: April 1, 2021
• Primary Completion: October 1, 2021
• Study Completion: January 31, 2022
• Last Updated: March 2, 2022

Record last verified: 2022-03

Locations

GR (1)