Systemic Treatment of Moderate-to-severe Psoriasis in Adults: Update of the French Guidelines

NCT05144165 | Unknown

• 1 other identifier: CDPDelphiPso
• Study Type: observational
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

French guidelines on the use of systemic treatments for moderate-to-severe psoriasis in adults have been developed by the psoriasis research group of the French Society of Dermatology using literature available until July 2017 (Amatore et al, 2019). Because several systemic treatments have been marketed since then, new guidelines are mandatory. The aim of this study coordinated by the Centre of Evidence of the French Society of Dermatology is to update the available French guidelines using a Delphi method.

Conditions

Psoriasis; Psoriasis Palmaris; Psoriasis Inverse; Psoriasis Vulgaris; Psoriatic Nail; Psoriatic Plaque; Psoriasis Guttate; Psoriasis of Scalp; Psoriasis Universalis; Psoriatic Erythroderma; Psoriasis Pustular

Keywords

Delphi; Consensus statement; Guidelines; Experts

Outcome Measures

Primary Outcomes (1)

• Update of the French guidelines by consensus using participating experts opinions

  Round 1 will include * 3 questions using an ordinal 7-point Likert scale, regarding every systemic treatment that could be prescribed as a first, second or subsequent line, in patients with moderate-to-severe plaque psoriasis without contra-indication to any treatment * 9 questions using an ordinal 7-point Likert scale, regarding first line therapeutic management of particular forms of psoriasis * 11 open-ended questions for special indications of each therapeutic agent. Round 2, 3 and 4 Experts will be asked to review the questionnaire based on the information provided in the former round. They will have to re-rate the 12 questions using the 7-point Likert scales. Regarding special indications for each therapeutic agent, expert's comments from round 1 will be synthesized and converted into MCQs for subsequent rounds. If consensus is reached for one question, the question will not reappear in subsequent rounds.

  15 days to complete the online survey for each round

Interventions

Experts consensus OTHER

Consensus opinion using Delphi Methodology

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Members of the Centre of Evidence (M. Beylot-Barry, G. Chaby, O. Chosidow, F. Corgibet, L. Fardet, B. Guillot, N. Jouan, D. Jullien) will propose a list of 40 to 50 French dermatologists experts in the field of psoriasis. Members of the scientific committees of the psoriasis research group (French Society of Dermatology) and "Resopso" will be included in the list of experts, with the exception of those participating of the design and publication of the present study.

You may qualify if:

• French dermatologists
• public and private practice practitioners
• members of the French Society of Dermatology
• expertise in the field of psoriasis

Sponsors & Collaborators

• Centre of Evidence of the French Society of Dermatology: lead

Study Sites (1)

Center of Evidence of Dermatology

Paris, 75009, France

RECRUITING

Related Publications (1)

• Amatore F, Villani AP, Tauber M, Viguier M, Guillot B; Psoriasis Research Group of the French Society of Dermatology (Groupe de Recherche sur le Psoriasis de la Societe Francaise de Dermatologie). French guidelines on the use of systemic treatments for moderate-to-severe psoriasis in adults. J Eur Acad Dermatol Venereol. 2019 Mar;33(3):464-483. doi: 10.1111/jdv.15340. Epub 2019 Feb 22.

  PMID: 30793796 RESULT

Related Links

• French Centre of Evidence in Dermatology

MeSH Terms

Conditions

Psoriasis; Guttate Psoriasis

Condition Hierarchy (Ancestors)

Skin Diseases, Papulosquamous; Skin Diseases; Skin and Connective Tissue Diseases

Central Study Contacts

Olivier CHOSIDOW, MD, PhD

CONTACT

olivier.chosidow@aphp.fr

Sophie LEDUCQ, MD

CONTACT

sophie.leducq@univ-tours.fr

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 21, 2021
• First Posted: December 3, 2021
• Study Start: November 8, 2021
• Primary Completion: March 31, 2022
• Study Completion: March 31, 2022
• Last Updated: December 3, 2021

Record last verified: 2021-11

Locations

FR (1)