NCT05143580

Brief Summary

This research is designed for experimental quantitative research and is conducted by simple random sampling. Both the control group and the experimental group provided preoperative routine nursing treatment and preoperative medical teaching manuals. The latter adds cognitive therapy and gamification evaluation. Both groups used CAM-ICU to assess the occurrence and duration of postoperative delirium, and DRS-R-98 was used to assess the severity of delirium. After collection, use SPSS 22.0 statistical software package for analysis and processing. The expected result is that the incidence of delirium, the duration of delirium, and the severity of delirium in the experimental group were significantly lower than those in the control group.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
120

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Dec 2021

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 28, 2021

Completed
1 month until next milestone

Study Start

First participant enrolled

December 1, 2021

Completed
2 days until next milestone

First Posted

Study publicly available on registry

December 3, 2021

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 30, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 30, 2022

Completed
Last Updated

December 3, 2021

Status Verified

October 1, 2021

Enrollment Period

11 months

First QC Date

October 28, 2021

Last Update Submit

November 21, 2021

Conditions

Keywords

Delirium after cardiac surgeryCognitive therapyGamification

Outcome Measures

Primary Outcomes (3)

  • Incidence of delirium

    * First use the Richmond Restlessness and Sedation Scale (RASS) to assess the state of consciousness. RASS is a 10-point scale. +1 to +4 represent different levels of anxiety, 0 points represent alertness and calmness, and -1 to -5 represent different levels of sedation. * When the RASS score is between -3 and +4, then evaluate the Confusion Assessment Method for the intensive care unit (CAM-ICU). The CAM-ICU is a four-step assessment method with items on altered mental status or fluctuating course, inattention, and altered level of consciousness or disorganized thinking. * If the evaluation result is the following two combinations, the first combination is mental state change, inattention, and consciousness level change; the second combination is mental state change, inattention, and disorganized thinking. This means that the CAM-ICU is positive and delirium has occurred.

    After surgery, the patient was evaluated at 48 hours.

  • Duration of delirium

    \- When using the CAM-ICU assessment system, delirium occurs, and the time from the occurrence to the end of the delirium will be recorded.

    Completed through delirium, an average of one month.

  • Severity of delirium

    * When delirium occurs, use Delirium Rating Scale-Revised-98 (DRS-R-98) to score the severity of delirium symptoms. * DRS-R-98 has a total of 16 scoring items, including 13 delirium severity and 3 diagnosis items. The total score is up to 46 points, of which the highest severity is 39 points. The higher the score, the more serious. * Clinically, the total score ≥ 18 points or the severity score ≥ 15 points are used.

    When delirium occurs, assessment is conducted at 9 am every day until the end of delirium, an average of one month.

Study Arms (2)

Cognitive Therapy Group

EXPERIMENTAL

* The anesthesiologist will provide the patient with instructions for preoperative anesthesia. * The operating room nurses will introduce the operating room environment and surgical care instructions to the patient. * Provide a manual for disease health education. * Provide post-operative care and environmental imaging materials, explain the importance of intensive care unit routines and related equipment, indwelling pipelines, related nursing staff, post-operative care methods, and provide imaging and health education manuals for explanation. * Use gamification to evaluate: pain relief skills, lung expansion skills.

Behavioral: Cognitive therapy

Routine Care Group

PLACEBO COMPARATOR

* The anesthesiologist will provide the patient with instructions for preoperative anesthesia. * The operating room nurses will introduce the operating room environment and surgical care instructions to the patient. * Provide a manual for disease health education.

Behavioral: Routine care

Interventions

* The anesthesiologist will provide the patient with instructions for preoperative anesthesia. * The operating room nurses will introduce the operating room environment and surgical care instructions to the patient. * Provide a manual for disease health education. * Provide post-operative care and environmental imaging materials, explain the importance of intensive care unit routines and related equipment, indwelling pipelines, related nursing staff, post-operative care methods, and provide imaging and health education manuals for explanation. * Use gamification to evaluate: pain relief skills, lung expansion skills.

Cognitive Therapy Group
Routine careBEHAVIORAL

* The anesthesiologist will provide the patient with instructions for preoperative anesthesia. * The operating room nurses will introduce the operating room environment and surgical care instructions to the patient. * Provide a manual for disease health education.

Routine Care Group

Eligibility Criteria

Age20 Years - 80 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Expected to undergo traditional thoracotomy or minimally invasive surgery for cardiac surgery.
  • No cognitive impairment before surgery.

You may not qualify if:

  • Diagnosed with aortic dissection.
  • Previously admitted to the intensive care unit.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Interventions

Cognitive Behavioral Therapy

Intervention Hierarchy (Ancestors)

Behavior TherapyPsychotherapyBehavioral Disciplines and Activities

Central Study Contacts

Huang ShuPing, Professor

CONTACT

Ke MengZhun, Master

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Model Details: Acceptance conditions: Patients who are expected to undergo traditional thoracotomy or minimally invasive surgery for cardiac surgery, and those who are over 20 years old and have no cognitive impairment before surgery. Excluded conditions: patients diagnosed with aortic dissection, over 80 years of age, and previously admitted to the intensive care unit.
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 28, 2021

First Posted

December 3, 2021

Study Start

December 1, 2021

Primary Completion

October 30, 2022

Study Completion

October 30, 2022

Last Updated

December 3, 2021

Record last verified: 2021-10