NCT05139641

Brief Summary

Multidisciplinary shared decision making of fertility preservation in Young womenwith Breast Cancer (MYBC): A Pragmatic stepped wedge cluster randomised trial

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
4,100

participants targeted

Target at P75+ for not_applicable

Timeline
31mo left

Started Dec 2021

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress63%
Dec 2021Dec 2028

First Submitted

Initial submission to the registry

November 17, 2021

Completed
14 days until next milestone

First Posted

Study publicly available on registry

December 1, 2021

Completed
Same day until next milestone

Study Start

First participant enrolled

December 1, 2021

Completed
6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2027

Expected
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2028

Last Updated

December 1, 2021

Status Verified

November 1, 2021

Enrollment Period

6 years

First QC Date

November 17, 2021

Last Update Submit

November 17, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • selection ratio of fertility preservation procedure

    selection ratio of fertility preservation procedure from Baseline to six years

Secondary Outcomes (1)

  • The success rate of pregnancy

    The success rate of pregnancy from Baseline to six years

Study Arms (3)

control group

PLACEBO COMPARATOR
Behavioral: Counseling to preserve fertility

counseling theraphy

EXPERIMENTAL
Behavioral: Counseling to preserve fertility

Retrospective data

NO INTERVENTION

Interventions

Counseling to preserve fertility VS Control group

control groupcounseling theraphy

Eligibility Criteria

Age19 Years - 40 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Women aged 19 to 40 years old
  • A person diagnosed with breast cancer by biopsy
  • Those who don't have evidence of distant metastasis
  • Eastern Cooperative Oncology Group(ECOG) performance status: 0-2 score
  • Before registering for clinical trials, chemotherapy, radiation therapy, anti-hormone therapy, immunotherapy, and surgery are not performed
  • A person who has fully understood and listened to the explanation of this clinical trial and then gave written consent

You may not qualify if:

  • Histologically, a person diagnosed with follicular or sarcoma
  • Those with a history of breast cancer (including recurrent breast cancer)
  • A person diagnosed with another cancer before breast cancer
  • A person diagnosed with metastatic breast cancer
  • A person who has a mental illness and has a hard time understanding clinical trials
  • Those who plan to conduct follow-up observation elsewhere(to change of hometowm)
  • Menopausal factors without menstruation after more than a year from the last menstrual date
  • A pregnant woman
  • Inappropriate for participation in clinical trials

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Medical Excellence

Seoul, South Korea

Location

Related Publications (1)

  • Baek SY, Kim HK, Park S, Yu JH, Lee MH, Youn HJ, Kim HA, Han JH, Choi JE, Lee JR, Lee KH, Chung S, Chae HD, Kim S, Yoo S, Hahm SK, Kim HJ. Multidisciplinary Shared Decision Making for Fertility Preservation in Young Women With Breast Cancer. J Breast Cancer. 2023 Dec;26(6):582-592. doi: 10.4048/jbc.2023.26.e44. Epub 2023 Oct 11.

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 17, 2021

First Posted

December 1, 2021

Study Start

December 1, 2021

Primary Completion (Estimated)

December 1, 2027

Study Completion (Estimated)

December 1, 2028

Last Updated

December 1, 2021

Record last verified: 2021-11

Locations