Emergency Pancreaticoduodenectomy: a Non-trauma Center Case Series

NCT05139394 | Completed

• 1 other identifier: EPD - CS
• Study Type: observational
• Target: 4
• Locations: 0 countries
• Sites: N/A

Brief Summary

Pancreaticoduodenectomy is a challenging procedure itself, being even more complex and demanding in emergency settings. Only a few cases of emergency pancreaticoduodenectomy (EPD) are reported in medical literature, usually performed for complex pancreaticoduodenal lesions. EPD has first been mentioned in trauma settings, even fewer cases being reported for non-traumatic indications. The investigators intend to present our experience with this intervention, in a non-trauma surgical centre. Our study is a prospective consecutive case series, that included patients that underwent emergency pancreaticoduodenectomy from January 2014 to May 2021. Data was collected from the electronic system database. The investigators collected data regarding the demographic characteristics of the patients, their medical history, preoperative and postoperative investigations (including blood work and imagistic investigations), surgery related information and postoperative evolution.

Conditions

Emergencies; Pancreas Disease

Outcome Measures

Primary Outcomes (5)

• Intraoperative blood loss

  ml of blood

  The length of the surgical intervention (an average of 3 hours)

• Operative time

  minutes of operating time

  The length of the surgical intervention (an average of 3 hours)

• In-hospital Morbidity

  Up to 90 days. Through study completion, during the hospital admission period

• In-hospital Mortality

  Up to 90 days. Through study completion, during the hospital admission period

• Long-term evolution

  It will be measured the overall survival time, number of readmissions and number of reinterventions

  The date of the last follow-up information was August 2021

Interventions

emergency pancreaticoduodenectomy PROCEDURE

Emergency pancreaticoduodenectomy (EPD) is a complex surgical procedure, that can be performed for complex pancreaticoduodenal injuries, that cannot be controlled through less invasive procedures. EPD can be performed either as a classical Whipple procedure, or as a pylorus-preserving procedure. A one stage procedure implies the reconstruction step being done in the same surgical intervention, while a two step procedure implies the reconstruction being done in a later stage, through a second surgical intervention.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients operated in Regional Institute of Gastroenterology and Hepatology Prof. Dr. O. Fodor Cluj-Napoca January 2014 and May 2021

You may qualify if:

• Emergency pancreaticoduodenectomy performed

You may not qualify if:

• Elective surgery
• Insufficient data

Sponsors & Collaborators

• Iuliu Hatieganu University of Medicine and Pharmacy: lead

MeSH Terms

Conditions

Emergencies; Pancreatic Diseases

Condition Hierarchy (Ancestors)

Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Digestive System Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: September 29, 2021
• First Posted: December 1, 2021
• Study Start: January 1, 2014
• Primary Completion: September 1, 2021
• Study Completion: September 1, 2021
• Last Updated: December 1, 2021

Record last verified: 2021-11