Is Invasive ICU-treatment Associated With Mental Illness?

NCT05137977 | Completed

• 1 other identifier: RBM2021
• Study Type: observational
• Target: 1,048,576
• Locations: 0 countries
• Sites: N/A

Brief Summary

Understanding long-term complications after intensive care is important to be able to offer prophylactic and therapeutic measures to post-intensive care unit (ICU) patients. Since patients in the ICU experience life threatening conditions, severe psychological and physical stress, we hypothesized that patients after ICU have an increased risk of mental illnesses specifically anxiety disorders, depression and post-traumatic stress disorder (PTSD). Moreover, we hypothesized that the prevalence and severity of mental illnesses are related to the extent of intensive care. Our endpoints are the prevalence of anxiety disorders, depression one year after ICU-care and if the extent of intensive care an independent predictor of psychiatric illness one year after ICU admission. We will assess Swedish Intensive Care registry data for all adult ICU patients admitted between 2010-2015 and assess ICD-10 codes for anxiety disorders, depression and PTSD one year after ICU admission.

Conditions

Postintensive Care Syndrome; Anxiety Disorder; Depression; PTSD; PICS; Intensive Care Psychiatric Disorder

Outcome Measures

Primary Outcomes (1)

• Mental illness

  Defined as PTSD, depressive symptoms or anxiety or combination of the earlier mentioned.

  2010-2015

Study Arms (1)

SIR

All adult intensive care patients. Data from the The Swedish intensive care registry

Procedure: Intensive Care

Interventions

Intensive Care PROCEDURE

Invasive ventilation more than 24hs.

Also known as: CRRT, Invasive ventilation

SIR

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Nationwide registry of patients admitted to ICU treatment in Sweden.

You may qualify if:

• years old

You may not qualify if:

• ICD codes for previous mental illness.
• ICU stay less than 24 hours

Sponsors & Collaborators

• Uppsala University: lead

MeSH Terms

Conditions

postintensive care syndrome; Anxiety Disorders; Depression; Stress Disorders, Post-Traumatic

Interventions

Critical Care; Noninvasive Ventilation

Condition Hierarchy (Ancestors)

Mental Disorders; Behavioral Symptoms; Behavior; Stress Disorders, Traumatic; Trauma and Stressor Related Disorders

Intervention Hierarchy (Ancestors)

Patient Care; Therapeutics; Health Services; Health Care Facilities Workforce and Services; Respiration, Artificial; Airway Management; Respiratory Therapy

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: OTHER
• Target Duration: 1 Year
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 16, 2021
• First Posted: November 30, 2021
• Study Start: January 1, 2010
• Primary Completion: December 31, 2015
• Study Completion: December 31, 2015
• Last Updated: November 30, 2021

Record last verified: 2021-11