NCT05135169

Brief Summary

Echocardiographic contrast will be administered to volunteers for the purpose of measuring transit time through various organs/vascular beds

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
16

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Mar 2022

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 2, 2021

Completed
24 days until next milestone

First Posted

Study publicly available on registry

November 26, 2021

Completed
3 months until next milestone

Study Start

First participant enrolled

March 3, 2022

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 16, 2023

Completed
2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2025

Completed
Last Updated

July 9, 2025

Status Verified

July 1, 2024

Enrollment Period

1.3 years

First QC Date

November 2, 2021

Last Update Submit

July 3, 2025

Conditions

Healthy

Outcome Measures

Primary Outcomes (1)

  • transit time

    time it takes for contrast to traverse an organ

    during procedure

Study Arms (1)

Contrast administration

Drug: Definity Suspension for Injection

Interventions

Definity Suspension for InjectionDRUG

Administration of Definity

Contrast administration

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Cross-section of VHVI faculty and sonographers

You may qualify if:

  • at least 18 years old
  • able to give informed consent

You may not qualify if:

  • Known allergic reaction to Definity ultrasound contrast
  • Pregnancy/Nursing - as assessed/disclosed by the participant

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

VUMC

Nashville, Tennessee, 37232, United States

Location

MeSH Terms

Interventions

Injections

Intervention Hierarchy (Ancestors)

Drug Administration RoutesDrug TherapyTherapeutics

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

November 2, 2021

First Posted

November 26, 2021

Study Start

March 3, 2022

Primary Completion

June 16, 2023

Study Completion

June 30, 2025

Last Updated

July 9, 2025

Record last verified: 2024-07

Data Sharing

IPD Sharing
Will not share

Locations

US(1)