NCT05132478

Brief Summary

118 adults with benign thyroid nodules who were seen at a UW Health clinic for a fine needle biopsy and do not need surgery will be enrolled and can expect to be on study for a one-time visit of up to 60 minutes. Each participant will be randomized to watch one of two videos simulating a patient-surgeon discussion about treatment options for low-risk thyroid cancer with or without emotionally supportive statements.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
126

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Nov 2021

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 12, 2021

Completed
5 days until next milestone

Study Start

First participant enrolled

November 17, 2021

Completed
7 days until next milestone

First Posted

Study publicly available on registry

November 24, 2021

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 7, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 7, 2023

Completed
1.2 years until next milestone

Results Posted

Study results publicly available

April 3, 2024

Completed
Last Updated

April 3, 2024

Status Verified

April 1, 2024

Enrollment Period

1.2 years

First QC Date

November 12, 2021

Results QC Date

January 26, 2024

Last Update Submit

April 2, 2024

Conditions

Keywords

thyroid cancerlow-riskthyroidectomyemotional supporttreatment

Outcome Measures

Primary Outcomes (1)

  • Treatment Choice

    The investigators will measure which treatment participants would choose if they were the patient with thyroid cancer in the video (total thyroidectomy or lobectomy) immediately after they finish watching the video.

    post video intervention (up to 60 minutes during the only study visit)

Secondary Outcomes (5)

  • Participant Decisional Confidence Score

    post video intervention (up to 60 minutes during the only study visit)

  • State Trait Anxiety Inventory Brief (STAI Brief) Score

    measured at baseline and after video intervention (during 1 day study visit)

  • Adapted Thyroid Cancer Fear Scale Score

    measured at baseline and after video intervention (during 1 day study visit)

  • Adapted Jefferson Scale of Patient's Perceptions of Physician's Empathy Score

    post video intervention (up to 60 minutes during the only study visit)

  • Adapted Trust in Physician Scale Score

    post video intervention (up to 60 minutes during the only study visit)

Study Arms (2)

Standard Video

ACTIVE COMPARATOR

A video simulation of a patient-surgeon discussion about treatment options for low-risk thyroid cancer WITHOUT emotionally supportive statements

Other: Standard Video

Emotionally Supportive Video

EXPERIMENTAL

A video simulation of a patient-surgeon discussion about treatment options for low-risk thyroid cancer WITH emotionally supportive statements

Other: Emotionally Supportive Video

Interventions

The video is approximately 6 1/2 minutes in length and portrays an emotionally supportive conversation between a patient and surgeon during which the surgeon discusses: the diagnosis, prognosis, available treatment options, benefits and harms of the options, and need for decision making. The surgeon speaks for the majority of the simulated visit and discusses total and hemi-thyroidectomy with the addition of emotionally supportive statements and gestures.

Emotionally Supportive Video

The video is approximately 5 minutes in length and portrays a standard conversation between a patient and surgeon during which the surgeon discusses: the diagnosis, prognosis, available treatment options, benefits and harms of the options, and need for decision making. The surgeon speaks for the majority of the simulated visit and discusses total and hemi-thyroidectomy.

Standard Video

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Seen in a UW Health Clinic for fine needle aspiration (FNA) of a thyroid nodule in the last 30 days
  • Thyroid nodule measures ≤4 centimeters
  • Benign thyroid nodule biopsy result
  • Able to speak and read English
  • Access to internet
  • Seen in a UW Health Clinic for FNA of a thyroid nodule in the last 30 days

You may not qualify if:

  • Additional thyroid nodule biopsy results that are not benign
  • History of thyroid cancer
  • History of thyroid surgery
  • Has seen a surgeon about thyroid or parathyroid surgery
  • Has a referral to see a surgeon about thyroid surgery
  • Deaf
  • Blind
  • Vulnerable populations such as prisoners
  • History of thyroid cancer
  • History of thyroid surgery
  • Has seen a surgeon about thyroid or parathyroid surgery
  • Plans to see a surgeon about thyroid surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Wisconsin Carbone Cancer Center

Madison, Wisconsin, 53792, United States

Location

MeSH Terms

Conditions

Thyroid NeoplasmsThyroid Nodule

Condition Hierarchy (Ancestors)

Endocrine Gland NeoplasmsNeoplasms by SiteNeoplasmsHead and Neck NeoplasmsEndocrine System DiseasesThyroid Diseases

Results Point of Contact

Title
Corrine Voils, PhD
Organization
UW School of Medicine and Public Health

Study Officials

  • Corrine Voils, PhD

    UW School of Medicine and Public Health

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 12, 2021

First Posted

November 24, 2021

Study Start

November 17, 2021

Primary Completion

February 7, 2023

Study Completion

February 7, 2023

Last Updated

April 3, 2024

Results First Posted

April 3, 2024

Record last verified: 2024-04

Data Sharing

IPD Sharing
Will share

Data collected for this study will be transferred and analyzed at the University of Michigan. After the study is completed, the de-identified, archived data may be transmitted to and stored at a data repository for use by other researchers including those outside of the study. Permission to transmit data to the University of Michigan and data repository will be included in the informed consent.

Shared Documents
STUDY PROTOCOL, SAP, ICF
Time Frame
After the completion of the primary endpoint.

Locations