NCT05131100

Brief Summary

Non-interventional observational study, to identify safety and effectiveness of Somavert during the post-marketing period based on the Korean RMP as required by the regulations of Ministry of Food and Drug Safety (MFDS)

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
5mo left

Started Jul 2022

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress91%
Jul 2022Sep 2026

First Submitted

Initial submission to the registry

November 10, 2021

Completed
13 days until next milestone

First Posted

Study publicly available on registry

November 23, 2021

Completed
8 months until next milestone

Study Start

First participant enrolled

July 13, 2022

Completed
4.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 15, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 15, 2026

Last Updated

July 4, 2025

Status Verified

July 1, 2025

Enrollment Period

4.2 years

First QC Date

November 10, 2021

Last Update Submit

July 2, 2025

Conditions

Keywords

acromegaly, Somavert, Post-Marketing Surveillance

Outcome Measures

Primary Outcomes (1)

  • Number of participants who experience adverse events

    Baseline through 28 days after last dose (approximately 52 weeks)

Secondary Outcomes (1)

  • Number of participants who experience Clinical Improvement as assessed by investigator

    Baseline through approximately 52 weeks

Study Arms (1)

Participants receiving Somavert

Drug: Somavert

Interventions

As provided in real world practice

Participants receiving Somavert

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Adult acromegaly patients who have had an inadequate response to surgery and/or radiation therapy and in whom appropriate medical treatment with somatostatin analogues did not normalize IGF-1 concentrations or was not tolerated

You may qualify if:

  • All patients who have been prescribed as per local label and investigators' judgement under the setting of routine practice in Korea who are eligible.

You may not qualify if:

  • Patients who are contraindicated for Somavert

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Pfizer

Seoul, 01037, South Korea

RECRUITING

Related Links

MeSH Terms

Conditions

Acromegaly

Interventions

pegvisomant

Condition Hierarchy (Ancestors)

Bone Diseases, EndocrineBone DiseasesMusculoskeletal DiseasesHyperpituitarismPituitary DiseasesHypothalamic DiseasesBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesEndocrine System Diseases

Study Officials

  • Pfizer CT.gov Call Center

    Pfizer

    STUDY DIRECTOR

Central Study Contacts

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 10, 2021

First Posted

November 23, 2021

Study Start

July 13, 2022

Primary Completion (Estimated)

September 15, 2026

Study Completion (Estimated)

September 15, 2026

Last Updated

July 4, 2025

Record last verified: 2025-07

Data Sharing

IPD Sharing
Will not share

Pfizer will provide access to individual de-identified participant data and related study documents (e.g. protocol, Statistical Analysis Plan (SAP), Clinical Study Report (CSR)) upon request from qualified researchers, and subject to certain criteria, conditions, and exceptions. Further details on Pfizer's data sharing criteria and process for requesting access can be found at: https://www.pfizer.com/science/clinical\_trials/trial\_data\_and\_results/data\_requests.

Locations