NCT05129072

Brief Summary

This objective of this clinical study aims to confirm whether multiple kalifilcon A daily disposable toric contact lenses are providing the intended level of spherical aberration correction when worn.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
75

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Aug 2021

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 25, 2021

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 24, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 24, 2021

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

November 10, 2021

Completed
12 days until next milestone

First Posted

Study publicly available on registry

November 22, 2021

Completed
3.6 years until next milestone

Results Posted

Study results publicly available

June 24, 2025

Completed
Last Updated

June 24, 2025

Status Verified

June 1, 2025

Enrollment Period

1 month

First QC Date

November 10, 2021

Results QC Date

February 9, 2023

Last Update Submit

June 20, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Spherical Aberration Measurement

    Spherical aberration (SA) occurs when light rays entering at different points of a spherical lens are not focused to the same point of the optical axis.

    60 minutes

Secondary Outcomes (1)

  • Visibility of Toric Etch Mark by the Investigator

    60 minutes

Study Arms (1)

kalifilcon A Daily Disposable Toric LD213001 lens

EXPERIMENTAL

kalifilcon A Daily Disposable Toric LD213001 lens in SKUs +6D, +3D, 0D, -3D, -6D, and -9D

Device: kalifilcon A Daily Disposable Toric LD213001 lens in SKUs +6D, +3D, 0D, -3D, -6D, and -9D

Interventions

kalifilcon A Daily Disposable Toric LD213001 lens

kalifilcon A Daily Disposable Toric LD213001 lens

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Be 18 years or older on the date the Informed Consent Form (ICF) is signed and have capacity to read, understand and provide written voluntary informed consent.
  • Have physiologically normal anterior segments not exhibiting clinically significant biomicroscopy findings.
  • Have no active ocular disease or allergic conjunctivitis.
  • Not be using any topical ocular medications.
  • Be willing and able to follow instructions.
  • Have signed a statement of informed consent.

You may not qualify if:

  • Participating in a conflicting study in the opinion of the Investigator.
  • Considered by the Investigator to not be a suitable candidate for participation.
  • A women of childbearing potential (those who are not surgically sterilized or postmenopausal) are excluded from participation in the investigation if they meet any one of the following conditions: she is currently pregnant, she plans to become pregnant during the study, she is breastfeeding.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bausch and Lomb Site 01

Rochester, New York, 14609, United States

Location

Results Point of Contact

Title
Steffen Robert, Senior Director Clinical Affairs
Organization
Bausch + Lomb Incorporated

Study Officials

  • Jeffery Schafer, OD

    Bausch & Lomb Incorporated

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 10, 2021

First Posted

November 22, 2021

Study Start

August 25, 2021

Primary Completion

September 24, 2021

Study Completion

September 24, 2021

Last Updated

June 24, 2025

Results First Posted

June 24, 2025

Record last verified: 2025-06

Locations