Textural Analysis of Mandibular Trabecular Bone Based on Grey Level Co-occurrence Matrix Features in Correlation With Age and Gender of an Egyptian Population Sample: A Cross-sectional Study Using Cone Beam CT

NCT05128565 | Unknown

• 1 other identifier: ORAD 7.2.1
• Study Type: observational
• Target: 22
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim of this study is to investigate if GLCM texture features are correlated with age-gender trabecular bone variations in different regions of interest on mandibular CBCT scans. This correlation will help in guiding the future selection of textural features and anatomical regions suitable for developing a potential screening method for age and sex related skeletal disorders.

Conditions

Visual Pattern Recognition

Keywords

texture analysis; texture features; cancellous bone

Outcome Measures

Primary Outcomes (1)

• Grey level co-occurrence matrix texture features

  Grey level co-occurrence matrix textural features (Entropy- Contrast-Angular second moment-Correlation-Sum of squares-Inverse difference moment-Sum of averages-Sum of variance-Sum of entropy-Difference of variance-Difference of entropy)

  Through study completion, an average of 18 months

Secondary Outcomes (1)

• Correlation

  Through study completion, an average of 18 months

Study Arms (4)

Females under 40

females from 18 years old to 40 years old

Males under 40

males from 18 years old to 40 years old

Females above 40

females older than 40 years old

Males above 40

males older than 40 years old

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Eligible mandibular CBCT scans of adult Egyptian population performed for any diagnostic reason other than this study will be retrieved from the database of oral and maxillofacial radiology department, faculty of dentistry, Cairo University.

You may qualify if:

• Mandibular CBCT scans of an acceptable quality (devoid of imaging artifacts).
• Egyptian male or female patients older than 18 years old.
• Trabecular bone is free of pathology.
• Teeth are present at the region of interest

You may not qualify if:

• Low quality CBCT scans.
• CBCT scans not including region of interest.
• CBCT scans for patients less than 18 years old.
• Trabecular bone is affected by osteolytic or osteoblastic bone pathologies.
• The region of interest is apical to a missing tooth or a restored tooth.

Sponsors & Collaborators

• Cairo University: lead

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor of oral and maxillofacial radiology

Study Record Dates

• First Submitted: November 3, 2021
• First Posted: November 22, 2021
• Study Start: December 1, 2021
• Primary Completion: June 1, 2023
• Study Completion: August 1, 2023
• Last Updated: November 22, 2021

Record last verified: 2021-11