Treatment In Acute Benign Paroxysmal Positional Vertigo

NCT05127694 | Completed

• 1 other identifier: 10840098-604.01.01-E.19383
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Benign paroxysmal positional vertigo (BPPV) is a vestibular disorder that manifests itself as a result of dizziness caused by the otoconia in the inner ear coming out of their places and circulating freely in the semicircular canals or by attaching to the cupula and sensitizing the cupula to head movements against gravity. The aim of the study is to compare the effectiveness of pharmacological treatment initiated by the physician and vestibular rehabilitation initiated by physiotherapist in patients with acute benign paroxysmal positional vertigo (BPPV). Thirty patients, aged 18-50 years, who applied to the Bağcılar Safa Hospital, were included in the study. The patients were divided into two groups, 15 pharmacological control group and 15 vestibular rehabilitation group. 8 patients in the pharmacological control group were given the drug containing betahistine by the physician, and 7 patients received the drug containing additional dimenhydrinate to the betahistine. In the rehabilitation group, exercises including head and eye movements and maneuvering were performed according to the direction of the canal after the exercise, and the patients were given a home exercise program. Treatment continued for 4 weeks. Visual Analogue Scale (VAS), dynamic visual acuity test, romberg, semitandem, tandem posture tests with a stopwatch, standing test on one leg with eyes open and closed, and unterberger tests were applied to patients before and after treatment.

Conditions

Benign Paroxysmal Positional Vertigo; Balance; Distorted; Vestibular Disorder; Dizziness

Keywords

Benign Paroxsymal Positional Vertigo; Balance; Pysiotherapy and Rehabilitation; Canalith Repositioning Procedure; Pharmacological Therapy; Dynamic Visual Acuity; Dizziness

Outcome Measures

Primary Outcomes (4)

• Perceptual Dizziness

  Perceived dizziness was assessed using the Visual Analog Scale (VAS). The patients stated the severity of their dizziness between 0-10 (0 being the mildest, 10 being unbearable).

  Four weeks

• Balance

  The balance of the patients was evaluated using the tandem, romberg, and one-leg standing test with eyes open and closed using a stopwatch. Individuals were expected to maintain their balance for 30 seconds.

  Four weeks

• Vestibular Dysfunction

  Vestibular Dysfunction was assessed with the Unterberger Test performed with the eyes closed. During the Unterberger test, the patient should marching where they are. If more than 45 degrees of deflection is detected, the test is positive.

  Four weeks

• Dynamic Visual Acuity

  Dynamic visual acuity was evaluated using the Snellen chart. A person taking the test is seated in a chair 2 meters away from the Snellen chart and while the therapist shakes the patient's head from right to left, the patient is asked if he can see the letters of each line, starting from the top. The test is terminated on the line where the letter sequence cannot be seen clearly.

  Four weeks

Study Arms (2)

Vestibular Rehabilitation Group

EXPERIMENTAL

Investigators applied vestibular rehabilitation in this group. This group was consist of 15 participants. After the evaluation investigators gave the patients repetitive vestibular exercises for 4 weeks and in the first week investigators performed canalith repositioning procedure depending on the affected canal. If affected posterior semicircular canal investigators applied Epley maneuver. If affected horizontal semicircular canal also applied barbeque roll maneuver.

Other: Vestibular Rehabilitation

Pharmacological Control Group

NO INTERVENTION

Investigators did not apply any treatment in this group. Participant in this group just used medications doctor-prescribed.

Interventions

Vestibular Rehabilitation OTHER

Vestibular Rehabilitation which is consist of repetitive exercises and canalit repositioning maneuvers

Vestibular Rehabilitation Group

Eligibility Criteria

• Age: 18 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• years of age,
• Positive Dix-Hallpike test result, and
• No spontaneous nystagmus.

You may not qualify if:

• Patients with Meniere's disease, vestibular neuritis, labyrinthitis, sudden sensory hearing loss, chronic otitis media, non-ambulatory patients, patients with vertigo due to central causes, and patients with cardiac complaints were excluded from the study.
• In addition, patients with conditions contraindicated for canalith repositioning procedures (such as cervical spine stenosis, severe kyphoscoliosis, cervical radiculopathy, ankylosing spondylitis, severe lumbar dysfunction, and spinal injuries) were excluded from the vestibular rehabilitation group.

Sponsors & Collaborators

• Istanbul Medipol University Hospital: lead

Study Sites (1)

Safa Hospital

Istanbul, Bagcilar, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Benign Paroxysmal Positional Vertigo; Vestibular Diseases; Dizziness

Condition Hierarchy (Ancestors)

Vertigo; Labyrinth Diseases; Ear Diseases; Otorhinolaryngologic Diseases; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Sensation Disorders

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Physiotherapist MSc, Lecturer

Study Record Dates

• First Submitted: October 6, 2021
• First Posted: November 19, 2021
• Study Start: July 1, 2019
• Primary Completion: December 8, 2019
• Study Completion: April 16, 2020
• Last Updated: December 2, 2021

Record last verified: 2021-11

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)