NCT05125497

Brief Summary

International prospective registry-based study of different types of In Vitro Fertilisation (IVF) and their outcome.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
3,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2022

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 3, 2021

Completed
15 days until next milestone

First Posted

Study publicly available on registry

November 18, 2021

Completed
1 month until next milestone

Study Start

First participant enrolled

January 1, 2022

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2023

Completed
Last Updated

May 15, 2023

Status Verified

May 1, 2023

Enrollment Period

1.2 years

First QC Date

November 3, 2021

Last Update Submit

May 12, 2023

Conditions

IVF

Outcome Measures

Primary Outcomes (1)

  • Implantation rate

    pregnancy rate per transferred embryo

    1 year

Secondary Outcomes (4)

  • Number of oocytes

    1 Year

  • Clinical pregnancy rate

    1 year

  • Pregnancy outcome

    1 year

  • In Vitro Fertilisation complications rates

    1 year

Study Arms (1)

In Vitro Fertilisation (IVF)-Patients

Patients aim to do In-Vitro-Fertilisation (IVF)

Procedure: In Vitro Fertilisation (IVF)

Interventions

In Vitro Fertilisation (IVF)PROCEDURE

Natural Cycle In Vitro Fertilisation (IVF): without hormonal stimulation Conventional In Vitro Fertilisation (IVF): conventional hormonal stimulation Minimal Stimulation In Vitro Fertilisation (IVF): low dose of hormonal stimulation will be applied

In Vitro Fertilisation (IVF)-Patients

Eligibility Criteria

Sexfemale(Gender-based eligibility)
Gender Eligibility Detailswomen
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients aiming to do In Vitro Fertilisation with fresh embryo transfer

You may not qualify if:

  • Medical freezing
  • Social freezing
  • thawed cycles

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Universitätsfrauenklinik Bern

Bern, 3000, Switzerland

Location

Related Publications (1)

  • Magaton IM, Siercks I, Nordin M, Popovici RM, Boogen EM, Eisenhardt S, Reeka N, Lanowski JS, Roumet M, von Wolff M. Oocyte and zygote development potential in minimal stimulation, natural cycle and conventionally stimulated IVF: an international multi-centre retrospective cohort study. J Assist Reprod Genet. 2025 Jul;42(7):2331-2340. doi: 10.1007/s10815-025-03508-3. Epub 2025 May 28.

    PMID: 40434705DERIVED

MeSH Terms

Interventions

Fertilization in Vitro

Intervention Hierarchy (Ancestors)

Reproductive Techniques, AssistedReproductive TechniquesTherapeuticsInvestigative Techniques

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
1 Year
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr. med. Isotta Martha Magaton

Study Record Dates

First Submitted

November 3, 2021

First Posted

November 18, 2021

Study Start

January 1, 2022

Primary Completion

March 31, 2023

Study Completion

March 31, 2023

Last Updated

May 15, 2023

Record last verified: 2023-05

Data Sharing

IPD Sharing
Will not share

Locations

CH(1)