NCT05124639

Brief Summary

Background. Self-management support is a complementary approach to treatment that aims to educate participants on the nature of anxiety and to improve their strategies to manage symptoms and well-being, thus presenting the potential to enhance recovery, improve outcomes, reduce recurrence rates and lower health care costs. There is limited evidence to support the effectiveness of group self-management support for anxiety disorders in community-based care. Objectives. This study aims at examining the effectiveness of a virtual group self-management support program (SMS) for anxiety disorders as an add-on to treatment-as-usual (TAU) in community-based care settings. We will also assess the incremental cost/effectiveness ratio and the implementability of the intervention. Methods. The trial is a pragmatic randomized controlled trial with a pre-treatment, post-treatment (4-month post-randomization), and follow-ups at 8, 12 and 24-months. Intervention. The experimental condition will consist of a 10-week SMS program for anxiety disorders in addition to TAU. The control condition will receive TAU without restrictions for anxiety disorders. Inclusion criteria will comprise being 18 years old or older, French-speaking, and presenting symptoms of anxiety disorders based on self-reported validated assessment scales. Patients will be recruited in the province of Quebec (Canada). Outcome measures: The primary outcome measure is the Beck Anxiety Inventory (BAI). The secondary outcome measures include self-reported instruments for anxiety and depressive symptoms, recovery, self-management, quality of life, and service utilisation. Statistical analysis: Intention-to-treat analysis. A mixed effects regression model will be used to account for between and within-subject variations in the analysis of the longitudinal effects of the intervention. Expected outcomes. The rigorous evaluation of the SMS intervention in the real world will provide information to decision makers, health care managers, clinicians and patients regarding the added value of group SMS for patients with anxiety disorders. Widespread implementation of this intervention could lead to more efficient mental health care services, to better long-term outcomes and to a significant reduction in the extensive social and economic burden of anxiety disorders.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
414

participants targeted

Target at P75+ for not_applicable

Timeline
7mo left

Started Oct 2022

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress85%
Oct 2022Dec 2026

First Submitted

Initial submission to the registry

October 27, 2021

Completed
22 days until next milestone

First Posted

Study publicly available on registry

November 18, 2021

Completed
11 months until next milestone

Study Start

First participant enrolled

October 6, 2022

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 16, 2024

Completed
2.8 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 21, 2026

Expected
Last Updated

May 9, 2024

Status Verified

May 1, 2024

Enrollment Period

1.4 years

First QC Date

October 27, 2021

Last Update Submit

May 7, 2024

Conditions

Keywords

Panic DisorderAgoraphobiaSocial Anxiety DisorderGeneralized Anxiety DisorderAnxiety disordersSelf-management support

Outcome Measures

Primary Outcomes (1)

  • Change in Beck Anxiety Inventory (BAI)

    Baseline and post-treatment (4-month post-randomization)

Secondary Outcomes (8)

  • Change in Beck Anxiety Inventory

    Baseline, post-treatment, and 8-month, 12-month, 24-month post-randomization follow-ups

  • Change in Generalised Anxiety Disorder-7

    Baseline, post-treatment, and 8-month, 12-month, 24-month post-randomization follow-ups

  • Change in Patient Health Questionnaire-9

    Baseline, post-treatment,12-month and 24-month post-randomization follow-ups

  • Change in Recovery Assessment Scale - Revised

    Baseline, post-treatment,12-month and 24-month post-randomization follow-ups

  • Change in Mental Health Self-Management Questionnaire

    Baseline, post-treatment,12-month and 24-month post-randomization follow-ups

  • +3 more secondary outcomes

Other Outcomes (2)

  • Gross Cohesion Scale

    During the 10-week SMS program, after sessions 3 and 8 (for experimental arm participants)

  • Working Alliance Inventory

    During the 10-week SMS program, after sessions 3 and 8 (for experimental arm participants)

Study Arms (2)

Group self-management support

EXPERIMENTAL

Group self-management support program for anxiety disorders developped by Relief (https://myrelief.ca/).

Behavioral: Group self-management support program for anxiety disorders

Treatment-as-usual

NO INTERVENTION

Treatment-as-usual and a delayed intervention (if desired by participants) after the 12-month follow up

Interventions

The group SMS manualized program for anxiety disorders (https://monrelief.ca) aims at improving self-management capabilities through weekly 2.5-hours sessions with 10-15 patients over a 10-week period.This trial will focus solely on the virtual format of the program. The SMS program covers the following themes: getting to know your anxiety; building self-awareness; reconsidering your lifestyle habits; adopting a problem-solving method; avoidance and exposure; acceptance and committed action; seeing things differently; managing your emotions; receiving support from others; and consolidating your toolkit.

Also known as: SMS+TAU
Group self-management support

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • (1) aged 18 and over,
  • (2) fluent in spoken and written French,
  • (3) presence of symptoms of anxiety disorders based on self-reported validated assessment scales and semi-structured assessment interview,
  • (4) access to a computer or tablet connected to the internet with microphone and video camera

You may not qualify if:

  • (1) previous enrolment in the SMS intervention provided by Relief
  • (2) active suicidal intentions,
  • (3) severe depressive symptoms,
  • (4) active substance-related and addictive disorder,
  • (5) cognitive impairment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Université de Sherbrooke

Sherbrooke, Quebec, J1H 5N4, Canada

Location

Related Publications (1)

  • Roberge P, Houle J, Provost JR, Coulombe S, Beaudin A, Bower P, Lemyre FC, Drapeau M, Drouin MS, Hudon C, Provencher MD, Vasiliadis HM. A pragmatic randomized controlled trial of a group self-management support program versus treatment-as-usual for anxiety disorders: study protocol. BMC Psychiatry. 2022 Feb 21;22(1):135. doi: 10.1186/s12888-021-03675-4.

Related Links

MeSH Terms

Conditions

Panic DisorderAgoraphobiaPhobia, SocialGeneralized Anxiety DisorderAnxiety Disorders

Condition Hierarchy (Ancestors)

Mental DisordersPhobic Disorders

Study Officials

  • Pasquale Roberge, Ph.D.

    Université de Sherbrooke

    PRINCIPAL INVESTIGATOR
  • Janie Houle, Ph.D.

    Université du Québec a Montréal

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 27, 2021

First Posted

November 18, 2021

Study Start

October 6, 2022

Primary Completion

March 16, 2024

Study Completion (Estimated)

December 21, 2026

Last Updated

May 9, 2024

Record last verified: 2024-05

Data Sharing

IPD Sharing
Will share

The data that support the findings of this study will be available on request from the nominated principal investigator \[PR\]. The data will not be publicly available due to ethics approval restrictions.

Shared Documents
STUDY PROTOCOL

Locations