A Health Action Process Approach Online Intervention for People With Multiple Sclerosis

NCT05124522 | Active Not Recruiting

• 2 other identifiers: 18754RG-1706-27718
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to implement the person-centered internet-based Health Action Process Approach to promoting physical activity in people with Multiple Sclerosis (i.e., eHAPA-MS online intervention) and assess the intervention's effectiveness and adherence.

Conditions

Multiple Sclerosis

Keywords

Physical Activity; Internet-Based Intervention

Outcome Measures

Primary Outcomes (1)

• The Health Action Process Approach Battery

  The battery measures risk perception, exercise benefits, motivation, and volition. "change" is being assessed.

  Through study completion, an average of 1 month

Study Arms (2)

MSPA eClass

EXPERIMENTAL

Behavioral: MSPA eClass

Waiting list

NO INTERVENTION

Interventions

MSPA eClass BEHAVIORAL

An 8-week MS-HAPA Internet-based intervention

MSPA eClass

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• are 18 years old and above;
• any type of multiple sclerosis
• have not maintained 30 minutes of MVPA accumulated per day for 2 days of the week during the previous 6 months;
• be relapse-free for the past 30 days;
• show low risk for contraindications of physical activity indicated by no more than a single 'yes' response on the Physical Activity Readiness Questionnaire;
• be able to walk with or without an assistive device;
• are willing to be randomized to an intervention or control group, complete the surveys and questionnaires, and wear an accelerometer during the intervention period;
• have a reliable Internet access.

You may not qualify if:

• have a score \>14 for the leisure score index of the Godin Leisure-Time Exercise Questionnaire;
• No computer or mobile device access with the internet.
• Patient determined disease steps (PDDS) Score = 7 i.e., using a wheelchair or scooter most of the time, or PDDS Score = 8 being bedridden.
• Anyone living outside of the United States of America.
• Anyone who is unable to speak, read and write in English.
• not willing to be randomized to an intervention or control group, complete the surveys and questionnaires, and wear an accelerometer during the intervention period.

Sponsors & Collaborators

• University of Illinois at Urbana-Champaign: lead

Study Sites (1)

University of Illinois Urbana-Champaign

Champaign, Illinois, 61820, United States

Location

Related Publications (1)

• Chiu C, Sridharan V, Khaliji M, Sajib MRUZ, Gao X, Zackowski K. Patient-Centered, Theory-Based, Online Intervention to Promote a Physically Active Lifestyle for People With Multiple Sclerosis: Protocol for a Randomized Controlled Trial. JMIR Res Protoc. 2025 Jul 17;14:e66091. doi: 10.2196/66091.

  PMID: 40455827 DERIVED

MeSH Terms

Conditions

Multiple Sclerosis; Motor Activity

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases; Behavior

Study Officials

• Chungyi Chiu, PhD

  University of Illinois Urbana-Champaign

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: October 25, 2021
• First Posted: November 18, 2021
• Study Start: October 25, 2021
• Primary Completion: April 30, 2026
• Study Completion (Estimated): December 31, 2026
• Last Updated: August 24, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will share
• Shared Documents: CSR
• Time Frame: Anticipated December 2025

Locations

US (1)