Healthcare Provider Human Papillomavirus Education and Professional Skills Intervention

NCT05120869 | Completed

• 2 other identifiers: 83212U54MD007592-26
• Study Type: interventional
• Target: 178
• Locations: 1 country
• Sites: 2

Brief Summary

Healthcare providers (HCP) serving the El Paso U.S.-Mexico Border Region will be recruited to compare educational and professional skills interventions focused on the human papillomavirus (HPV). Our hypothesis is that improving provider knowledge and communication strategies about HPV and its vaccine will reduce hesitancy and increase uptake and completion among the populations they serve.

Conditions

Health Personnel Attitude; Health Knowledge, Attitudes, Practice

Keywords

Healthcare Professionals; Health Personnel Knowledge, Attitudes, Practices; Healthcare Skills and Training; Human Papillomavirus Vaccination; Human Papillomavirus Cancer Screening; HPV Cancer Prevention; HPV Cancer Mitigation; Sexual and Reproductive Health; U.S.-Mexico Border Health; Behavioral Research; Community Engaged Research; Health Disparities; Health Inequities; Social Determinants of Health; Coronavirus disease 2019 (COVID-19) Pandemic

Outcome Measures

Primary Outcomes (1)

• Between-group changes in proportions from post-intervention scores of the Healthcare Provider (HCP) Practices scale on the Healthcare Personnel Survey

  8-item HCP Practices scale (HCP vaccine recommendations, HCP screening recommendations, HCP communication practices) scored on a Likert scale from Never (1) to Always (5)

  immediately post-intervention (0 months), 3 months post-intervention, and 6 months post-intervention

Secondary Outcomes (2)

• Between-group changes in proportions from post-intervention scores of the Human Papillomavirus (HPV) Vaccine Attitudes scale on the Healthcare Personnel Survey

  immediately post-intervention (0 months), 3 months post-intervention, and 6 months post-intervention

• Between-group changes in proportions from post-intervention scores on the Human Papillomavirus (HPV) Knowledge scale on the Healthcare Personnel Survey

  immediately post-intervention (0 months), 3 months post-intervention, and 6 months post-intervention

Study Arms (2)

Treatment

EXPERIMENTAL

A tailored HPV education and professional skills intervention.

Behavioral: Tailored HPV Education and Professional Skills Intervention Group

Control

ACTIVE COMPARATOR

General/publicly available educational materials on HPV and communication skills.

Behavioral: General HPV Education and Communication Skills Control Group

Interventions

Tailored HPV Education and Professional Skills Intervention Group BEHAVIORAL

The provider education and professional skills intervention will involve audio and visual content and will be delivered in the English language.

Treatment

General HPV Education and Communication Skills Control Group BEHAVIORAL

The general provider education intervention will involve audio and visual content and will be delivered in the English language.

Control

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Current (in practice) or emerging (in training - medical student, resident, or fellow) healthcare provider
• Working/training or living in the El Paso U.S.-Mexico Border Region (i.e., El Paso County, TX-Southern New Mexico)
• Have the authorization to recommend/prescribe/administer the HPV vaccine

You may not qualify if:

• Unaffiliated with the El Paso U.S.-Mexico Border Region (i.e., El Paso County, TX-Southern New Mexico)
• Participation in Phases I or II of the larger research project \[cross-sectional phases\]
• Does not identify as a current or emerging healthcare provider
• Declines or is unable to participate in the full intervention and follow-up time-points
• Unable to complete participation and activities in the English language

Sponsors & Collaborators

• University of Texas, El Paso: lead
• National Institute on Minority Health and Health Disparities (NIMHD): collaborator
• Burrell College of Osteopathic Medicine: collaborator

Study Sites (2)

Burrell College of Osteopathic Medicine

Las Cruces, New Mexico, 88001, United States

Location

The University of Texas at El Paso, Border Biomedical Research Center

El Paso, Texas, 79968, United States

Location

Related Publications (4)

• Brabin L, Roberts SA, Farzaneh F, Kitchener HC. Future acceptance of adolescent human papillomavirus vaccination: a survey of parental attitudes. Vaccine. 2006 Apr 12;24(16):3087-94. doi: 10.1016/j.vaccine.2006.01.048. Epub 2006 Feb 9.

  PMID: 16500736 BACKGROUND

• McRee AL, Brewer NT, Reiter PL, Gottlieb SL, Smith JS. The Carolina HPV immunization attitudes and beliefs scale (CHIAS): scale development and associations with intentions to vaccinate. Sex Transm Dis. 2010 Apr;37(4):234-9. doi: 10.1097/OLQ.0b013e3181c37e15.

  PMID: 19940807 BACKGROUND

• Katz ML, Krieger JL, Roberto AJ. Human papillomavirus (HPV): college male's knowledge, perceived risk, sources of information, vaccine barriers and communication. J Mens Health. 2011 Oct 1;8(3):175-184. doi: 10.1016/j.jomh.2011.04.002.

  PMID: 21966351 BACKGROUND

• Martinez J, Cordero JI, Whitney M, LaRoche KL, Frietze G, Moya EM, Gosselink K. Web-Based Human Papillomavirus Education and Professional Skills Intervention for Health Care Providers: Protocol for a Randomized Controlled Trial. JMIR Res Protoc. 2025 Apr 3;14:e60790. doi: 10.2196/60790.

  PMID: 40179382 DERIVED

Related Links

• NIH RePORTER for 2U54MD007592-26 8321

MeSH Terms

Conditions

Behavior; Coitus; COVID-19

Condition Hierarchy (Ancestors)

Sexual Behavior; Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Study Officials

• Eva M Moya, PhD, LMSW

  The University of Texas at El Paso, Border Biomedical Research Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Masking Details: * Participants \[blinding\]: participants will be randomly assigned to treatment and control groups, they will not be made aware of other participant's receipt of treatment or control materials. Participants will be asked not to discuss this project outside of the intervention; delivery of the intervention or other educational materials will be virtual, limiting the ability of participants to interact with one another during the study. * Outcome assessor \[blinding\]: to reduce bias in the implementation and assessment of the clinical trial, participant information and pre-post survey responses will be maintained separately from the assignment and delivery of the intervention.
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Model Details: A parallel trial design will be used to examine the effectiveness of a tailored HPV education and professional skills intervention. Emerging and current healthcare providers will be randomly assigned to one of two conditions: 1) treatment condition in which they will receive a tailored Education and Professional Skills Intervention, and 2) control condition in which they will receive general, publicly available information about HPV and communication skills. Participants will then be followed over time and the responses will be compared between groups.

Study Record Dates

• First Submitted: October 6, 2021
• First Posted: November 15, 2021
• Study Start: December 22, 2023
• Primary Completion: December 2, 2024
• Study Completion: December 2, 2024
• Last Updated: September 4, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, ICF, CSR, ANALYTIC CODE
• Time Frame: Approximately, starting 6 months-post scholarly publication of previously listed primary and secondary study outcome(s).
• Access Criteria: Collected deidentified IPD and supporting information will be provided on a case by case basis following a formal request to the University of Texas at El Paso (UTEP) Institutional Review Board (IRB) and subsequent approval by the Principal Investigator.

Locations

US (2)