Can Subclavian / Infraclavicular Axillary Vein Collapsibility Index Predict Post-Spinal Hypotension in Caesarean Section Operations?

NCT05120258 | Unknown

• 1 other identifier: SCV
• Study Type: observational
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

Postspinal hypotension (PSH) is a common side effect with an incidence of 15.3% to 33%, which may result in organ hypoperfusion and ischemic events (1,2). In pregnant patients, this incidence may increase to 70% and severe PSH may increase the risk of maternal and fetal complications (3). Therefore, it is important for anesthesiologists to estimate the incidence of PSH in cesarean sections and to identify possible mechanisms (4). One of the important factors affecting the susceptibility of patients to intraoperative hypotension is the preoperative intravascular volume status. Recently, ultrasonography of the central veins has been used frequently by anesthesiologists in the preoperative period in order to evaluate the intravascular volume status (5). Salama and Elkashlan stated that the collapsibility index of the inferior vena cava is a new predictive value for PSH (6). Choi et al. showed that the subclavian vein or infraclavicular axillary vein collapsibility index is an important predictive value for hypotension after induction of general anesthesia (7). In this study, we wanted to investigate whether the subclavian vein or infraclavicular axillary vein collapsibility index can be used as a predictive value for PSH in cesarean section.

Conditions

Post Spinal Hypotension

Keywords

post spinal hypotension, the subclavian vein or infraclavicular axillary vein collapsibility index

Outcome Measures

Primary Outcomes (1)

• Predictive value of Subclavian / Infraclavicular Axillary Vein Collapsibility Index for detecting Postspinal hypotension

  Postspinal hypotension (PSH) is a common side effect with an incidence of 15.3 to 33% that may result in organ hypoperfusion and ischaemic events. This incidence is higher in pregnant women with a rate of 70%. Measurement of the IVC diameter and its collapsibility index before spinal anaesthesia has been shown to be a good predictive value of the occurrence of PSH. A previous study showed an acceptable correlation between the collapsibility of SCV (SCV-CI) and collapsibility of IVC (IVC-CI) in surgical and intensive care patients. In this study, we measured the preoperative collapsibility index of the SCV or the infraclavicular axillary vein during respiratory variation, and then examined whether these parameters could predict hypotension after spinal anaesthesia in patients undergoing ceserean

  45 min

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

ASA I-II physical status patients scheduled for cesarean section under spinal anesthesia

You may qualify if:

• Spinal anesthesia
• ceserean operation
• American Society of Anesthesiologists' (ASA) physical status I-II

You may not qualify if:

• Patients who underwent cesarean section in emergency conditions
• Patients who underwent cesarean section under general anesthesia
• American Society of Anesthesiologists' (ASA) physical status III-IV

Sponsors & Collaborators

• Selcuk University: lead

Study Officials

• Emine ASLANLAR, assis. prof.

  selcuk univercity medical faculty

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Emine ASLANLAR, assis. prof.

CONTACT

05556219830; draslanlar@gmail.com

Mehmet SARGIN, assoc. prof.

CONTACT

05322662766; mehmet21sargin@yahoo.com

Study Design

• Study Type: observational
• Observational Model: CASE CROSSOVER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant professor

Study Record Dates

• First Submitted: November 2, 2021
• First Posted: November 15, 2021
• Study Start: November 8, 2021
• Primary Completion: January 24, 2022
• Study Completion: March 2, 2022
• Last Updated: November 15, 2021

Record last verified: 2021-11