Clinical Pharmacist-led Appropriate Acid Suppression Therapy Stewardship Program
Impact of Clinical Pharmacist-led Appropriate Acid Suppression Therapy Stewardship Program on Hospitalized Older Patients: A Non-Randomized Controlled Study
1 other identifier
interventional
250
1 country
1
Brief Summary
To evaluate the impact of clinical pharmacist-led appropriate acid suppression therapy stewardship program in hospitalized older patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Sep 2019
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 1, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 28, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
August 31, 2021
CompletedFirst Submitted
Initial submission to the registry
October 17, 2021
CompletedFirst Posted
Study publicly available on registry
November 9, 2021
CompletedOctober 18, 2023
October 1, 2023
6 months
October 17, 2021
October 17, 2023
Conditions
Outcome Measures
Primary Outcomes (2)
Appropriateness of Proton Pump Inhibitors Usage
The rate of appropriateness use of proton pump inhibitors based on the guidelines at hospital stay
during hospital stay, an average of 14 days
Potentially Inappropriate Proton Pump Inhibitors Usage
The rate of potentially inappropriate use of proton pump inhibitors based on American Geriatric Society Beers Criteria© 2019
at discharge, an average of 14 days after admission to hospital
Secondary Outcomes (5)
Clinical outcome
1 year
Cost saving during hospital stay
during hospital stay, an average of 14 days
Medication Appropriateness Index for Proton Pump Inhibitors at hospital stay
during hospital stay, an average of 14 days
Cost saving after discharge
a month
Medication Appropriateness Index for Proton Pump Inhibitors at discharge
at discharge, an average of 14 days after admission to hospital
Study Arms (2)
Clinical pharmacist-led services
EXPERIMENTALClinical Pharmacist-led Appropriate Acid Suppression Therapy Stewardship Program
Control group
NO INTERVENTIONUsual care
Interventions
Clinical pharmacist provided medication reconciliation and medication review during the hospital stay.
Eligibility Criteria
You may qualify if:
- years old or greater
- Admitted to the hospital with any reason
- Ordered at least one PPI dose within 48 hours of admission
You may not qualify if:
- Transferred to another ward (including an intensive care unit)
- Having active gastrointestinal bleeding
- Having active malignity
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Marmara University
Istanbul, Turkey (Türkiye)
Related Publications (1)
Dumlu HI, Sancar M, Ozdemir A, Okuyan B. Impact of a clinical pharmacist-led stewardship program for the appropriate use of acid suppression therapy in older hospitalized patients: a non-randomized controlled study. Int J Clin Pharm. 2022 Aug;44(4):914-921. doi: 10.1007/s11096-022-01394-8. Epub 2022 Apr 21.
PMID: 35449351DERIVED
Study Officials
- PRINCIPAL INVESTIGATOR
Betul Okuyan
Marmara University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- HEALTH SERVICES RESEARCH
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assoc.Prof.
Study Record Dates
First Submitted
October 17, 2021
First Posted
November 9, 2021
Study Start
September 1, 2019
Primary Completion
February 28, 2020
Study Completion
August 31, 2021
Last Updated
October 18, 2023
Record last verified: 2023-10
Data Sharing
- IPD Sharing
- Will not share