Transcranial Ultrasound Screening of Nursery Unit Neonatesfor Brain Abnormalities
1 other identifier
observational
100
0 countries
N/A
Brief Summary
- To investigate the prevalence of cerebral abnormal findings in neonates admitted at nursery unit.{11}
- to identify the associated clinical features and to better target neonatal CUS investigations.{11}
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Dec 2021
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 28, 2021
CompletedFirst Posted
Study publicly available on registry
November 9, 2021
CompletedStudy Start
First participant enrolled
December 1, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
February 1, 2023
CompletedNovember 29, 2021
November 1, 2021
1 year
October 28, 2021
November 17, 2021
Conditions
Outcome Measures
Primary Outcomes (1)
Investigate the preavalence of cerebral abnormal findings in neonates
Cranial Ultrasound is performed with basic grayscale imaging
Baseline
Interventions
All neonates undergoing CUS at nursery unit at assiut university hospital. Cranial ultrasound is performed with basic grayscale imaging. For optimal resolution and good overview, a multifrequency (5-10 MHz) linear or convex sector transducer is used. Imaging is obtained through the anterior fontanel in the coronal and sagittal planes.{12,13} Typically, six to eight coronal images are obtained beginning at the frontal lobes just anterior to the frontal horns and extending to the occipital lobes posterior to the lateral ventricle trigones.{14} The transducer is then rotated 90°, and approximately five images are obtained, including a midline sagittal view of the corpus callosum and cerebellar vermis in addition to bilateral parasagittal images beginning in the midline and progressing laterally through the peripheral cortex.Doppler ultrasound may be added to assess ischemic areas.{13-15}
Eligibility Criteria
Neonates undergoing CUS at nursery unit at university hospital
You may qualify if:
- All neonates suspected clinically to be suffered from brain lesions at nursery unit at assiut university hospitals
You may not qualify if:
- Patients above the age of 28 days
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Maalouf EF, Duggan PJ, Counsell SJ, Rutherford MA, Cowan F, Azzopardi D, Edwards AD. Comparison of findings on cranial ultrasound and magnetic resonance imaging in preterm infants. Pediatrics. 2001 Apr;107(4):719-27. doi: 10.1542/peds.107.4.719.
PMID: 11335750BACKGROUND
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Resident Doctor
Study Record Dates
First Submitted
October 28, 2021
First Posted
November 9, 2021
Study Start
December 1, 2021
Primary Completion
December 1, 2022
Study Completion
February 1, 2023
Last Updated
November 29, 2021
Record last verified: 2021-11