Inappropriate Sinus Tachycardia Registry
A Multicenter Patient Registry for Outcomes of Inappropriate Sinus Tachycardia and Postural Orthostatic Tachycardia Syndrome Treatment
1 other identifier
observational
500
2 countries
10
Brief Summary
The primary objective of this registry is to capture real-world safety and performance data on AtriCure devices used to ablate cardiac tissue when treating Inappropriate Sinus Tachycardia (IST) or Postural Tachycardia Syndrome (POTS). This is a retrospective and prospective, multicenter, US/OUS, observational data registry.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Mar 2022
Longer than P75 for all trials
10 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 28, 2021
CompletedFirst Posted
Study publicly available on registry
November 4, 2021
CompletedStudy Start
First participant enrolled
March 1, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 1, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
January 1, 2027
October 20, 2025
September 1, 2025
4.8 years
October 28, 2021
October 16, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
AtriCure commercially available devices used to treat IST or POTS
The IST Registry will attempt to enroll all eligible patients at registry sites who have already had or are scheduled to have a procedure to treat IST/POTS that includes the use of at least one commercially available AtriCure cardiac ablation devices.
12 months
Interventions
Epicardial and endocardial hybrid ablation procedure used to treat the IST or POTS using AtriCure commercially available devices.
Eligibility Criteria
The IST registry eligibility is open to sites and physicians performing the described treatments for patients diagnosed with IST and POTS. Subjects must have been scheduled to undergo or have undergone the described treatments for IST or POTS by their physicians. Registry participating sites will enroll patients that meet all inclusion criteria and no exclusion criteria without preselection or bias.
You may qualify if:
- Subject is scheduled to undergo or has undergone a procedure to treat IST or POTS using one or more AtriCure devices.
- Subject is willing to provide written informed consent (defined as legally effective, documented confirmation of a subject's voluntary agreement to participate in this Registry) or authorization per institution and geographical requirements
You may not qualify if:
- Subject is enrolled in a concurrent study that may impact treatment outcome of IST or POTS.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- AtriCure, Inc.lead
Study Sites (10)
Stanford University
Palo Alto, California, 94305, United States
Sequoia Hospital
Redwood City, California, 94062, United States
University of Florida
Gainesville, Florida, 32608, United States
Sarasota Memorial Hospital
Sarasota, Florida, 34239, United States
Kansas City Cardiac Arrhythmia Research
Kansas City, Kansas, 64132, United States
MedStar Health Research Institute
Hyattsville, Maryland, 20782, United States
The Carl & Edyth Lindner Center for Research & Education at The Christ Hospital
Cincinnati, Ohio, 45219, United States
Texas Cardiac Arrhythmia Research Foundation
Austin, Texas, 78705, United States
Intermountain Medical Center
Murray, Utah, 84107, United States
Universitair Ziekenhuis Brussels
Brussels, Belgium
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- OTHER
- Target Duration
- 12 Months
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
October 28, 2021
First Posted
November 4, 2021
Study Start
March 1, 2022
Primary Completion (Estimated)
January 1, 2027
Study Completion (Estimated)
January 1, 2027
Last Updated
October 20, 2025
Record last verified: 2025-09
Data Sharing
- IPD Sharing
- Will not share