NCT05105932

Brief Summary

This is a prospective observational trial. The purpose of this study is to explore the feasibility of EIT monitoring pulmonary blood flow and the consistency and difference between EIT monitoring pulmonary local ventilation blood flow and SPECT and CTPA monitoring methods

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jan 2020

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2020

Completed
1.1 years until next milestone

First Submitted

Initial submission to the registry

January 28, 2021

Completed
9 months until next milestone

First Posted

Study publicly available on registry

November 3, 2021

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2023

Completed
Last Updated

November 3, 2021

Status Verified

October 1, 2021

Enrollment Period

3.4 years

First QC Date

January 28, 2021

Last Update Submit

October 24, 2021

Conditions

Pulmonary VentilationPulmonary Perfusion

Keywords

EITpulmonary perfusion

Outcome Measures

Primary Outcomes (2)

  • Regional pulmonary perfusion by EIT

    Using EIT to measure the regional pulmonary perfusion and calculate ventilation/perfusion ratio

    1 Day

  • Regional pulmonary perfusion by CTPA

    Using CTPA to measure the regional pulmonary perfusion and calculate ventilation/perfusion ratio

    1 Day

Secondary Outcomes (1)

  • Regional pulmonary ventilation index by EIT

    1 Day

Study Arms (2)

EIT group

patients went through EIT detection

CTPA group

patients went through CTPA detection

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients who need CTPA examination in the Department of nuclear medicine / radiology of Peking Union Medical College Hospital

You may qualify if:

  • Admission to ICU was less than 72 hours;
  • Age ≥ 18 years old and ≤ 80 years old;
  • Volunteer to participate after communicating with patients' family members;

You may not qualify if:

  • The patients with heart implants could not be monitored by EIT;
  • Patients or their families refused to participate in the study;
  • Hypernatremia

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Peking Union Medical College Hospital

Beijing, Beijing Municipality, China

RECRUITING

Study Officials

  • Yun Long

    Peking Union Medical College Hospital

    STUDY DIRECTOR

Central Study Contacts

Yun Long

CONTACT

13911608699ly_icu@aliyun.com

Siyi Yuan

CONTACT

15201518815yuansiyizqh@163.com

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 28, 2021

First Posted

November 3, 2021

Study Start

January 1, 2020

Primary Completion

June 1, 2023

Study Completion

June 1, 2023

Last Updated

November 3, 2021

Record last verified: 2021-10

Locations

CN(1)