The Impact of Synergies of Indoor Air Pollutants on Childhood Health and Wellbeing
SynAir-Child
1 other identifier
observational
3,000
0 countries
N/A
Brief Summary
To quantify health effects of synergizing chemical and biological pollutants in a targeted population setting, i.e., school-aged children. Indoor air pollutants will be monitored within the classrooms with high end sensors. Exposure data from additional sources (outdoor, home, transports) will be obtained. Health outcomes will be assessed prospectively using validated medical procedures and real-time tracking with mobile health (mHealth) equipment and a gamified computer app.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Sep 2023
Longer than P75 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
September 13, 2021
CompletedFirst Posted
Study publicly available on registry
November 3, 2021
CompletedStudy Start
First participant enrolled
September 1, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
September 1, 2027
November 3, 2021
October 1, 2021
3.5 years
September 13, 2021
October 22, 2021
Conditions
Outcome Measures
Primary Outcomes (8)
Respiratory, mental health
Questionnaires
One year
Immune health
RNA Sequency/CRP
One year
Oxidative stress
DNA damage levels in blood cells
One year
Lung function and
Spirometry
One year
Airway inflammation
Exhaled nitric oxide
One year
Exhaled volatile compounds
Breath biopsy
One year
Cardiovascular metrics
Wearables
One year
Height and weight
Height in cm and weight in kg will be combined to report BMI (kg/m\^2)
One year
Interventions
Monitor the indoor pollutants and their effect on children well being
Eligibility Criteria
Children at this age have the ability to understand the character of the study, to handle the app and the wearables, to successfully perform lung function and airway inflammation measurements (as it has been ascertained in the previous FP7\_PreDicta and Horizon\_CURE projects), to cooperate with blood sampling, while not being yet subjective to hormonal changes of puberty. Moreover, students at this age mainly attend lessons in the same class, thus exposures in the school environment are considered stable,
You may qualify if:
- Students of primary schools aged 8-9 years.
- The subject and/or legal custodian have the verbal, writing and mental ability to understand the intent and character of the study.
- Written informed consent from the child's parents/guardian's
You may not qualify if:
- Unwilling to use the application and follow the procedures of the protocol
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Biospecimen
Blood samples (optional)
Study Officials
- STUDY CHAIR
NIKOLAOS G PAPADOPOULOS, Professor
National and Kapodistrian Univeristy of Athens
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 1 Year
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- PROFESSOR
Study Record Dates
First Submitted
September 13, 2021
First Posted
November 3, 2021
Study Start
September 1, 2023
Primary Completion (Estimated)
March 1, 2027
Study Completion (Estimated)
September 1, 2027
Last Updated
November 3, 2021
Record last verified: 2021-10