NCT05094258

Brief Summary

Comparison of the early clinical and radiological results and patient satisfaction of the mobile and fixed insert unicondylar knee prostheses routinely used in the clinic.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P50-P75 for not_applicable knee-osteoarthritis

Timeline
Completed

Started Jun 2020

Typical duration for not_applicable knee-osteoarthritis

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2020

Completed
1.4 years until next milestone

First Submitted

Initial submission to the registry

October 13, 2021

Completed
13 days until next milestone

First Posted

Study publicly available on registry

October 26, 2021

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2021

Completed
11 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2022

Completed
Last Updated

November 30, 2021

Status Verified

November 1, 2021

Enrollment Period

1.5 years

First QC Date

October 13, 2021

Last Update Submit

November 24, 2021

Conditions

Keywords

Unicompartmental Knee osteoarthritisUnicompartmental Knee prosthesisMobile insertFixed İnsert

Outcome Measures

Primary Outcomes (2)

  • Short Form Health Survey (SF-36)

    SF-36 Score (0-100) to assess patient satisfaction at postoperative 1st year

    0-1 year

  • Knee injury and osteoarthritis outcome score (KOOS)

    Knee injury and osteoarthritis outcome score (0-100)

    0-1 year

Study Arms (2)

mobile insert

ACTIVE COMPARATOR

Unicondylar knee arthroplasty with mobile insert was applied to 30 patients determined by randomization. The patients were followed for 1 year.

Procedure: unicondylar knee prosthesis with mobile insert

fixed insert

ACTIVE COMPARATOR

Unicondylar knee arthroplasty with fixed insert was applied to 30 patients determined by randomization. The patients were followed for 1 year.

Procedure: unicondylar knee prosthesis with fixed insert

Interventions

Patients with unicondylar knee replacement using the mobile insert option

mobile insert

Patients with unicondylar knee replacement using the fixed insert option

fixed insert

Eligibility Criteria

Age45 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with degenerative knee arthritis with only one compartment affected

You may not qualify if:

  • Inflammatory Arthritis
  • Tricompartmental arthritis
  • Patients with fixed varus deformity greater than -10 degrees
  • Patients with fixed valgus deformity greater than -5 degrees
  • Patients with knee range of motion less than 90 degrees
  • Patients with more than 10 degrees of flexion contracture"

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Volkan Ezici

Istanbul, Fatih, 3344, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Osteoarthritis, Knee

Condition Hierarchy (Ancestors)

OsteoarthritisArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Masking Details
After collecting all data about patients and patients participating in the study, the independent person who will evaluate the data will be blinded.
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Patients with medial knee arthrosis will be randomized to receive unicompartmental knee prosthesis using mobile inserts in 30 patients and fixed inserts in 30 patients. Patients will be evaluated after at least 1 year of follow-up
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
orthopaedic surgeon

Study Record Dates

First Submitted

October 13, 2021

First Posted

October 26, 2021

Study Start

June 1, 2020

Primary Completion

December 1, 2021

Study Completion

November 1, 2022

Last Updated

November 30, 2021

Record last verified: 2021-11

Data Sharing

IPD Sharing
Will not share

Participant data will not be shared

Locations