Psychological Impact of COVID-19 on Intensive Care Survivors
PIM-COVID
The Psychological Impact of Surviving an Intensive Care Admission Due to Coronavirus Disease 2019 (COVID-19) on Patients in the United Kingdom
3 other identifiers
observational
1,620
1 country
50
Brief Summary
Psychological distress is commonly experienced by survivors of an intensive care admission, including patients treated during previous pandemics. Whilst data emerges about the short-term impact of COVID-19 on patients and healthcare systems, the long term impact remains unclear. The purpose of this trainee-led, multi-centre longitudinal study is to assess the short- and long-term psychological impact on patients who have survived an admission to intensive care due to COVID-19, and identify possible predictors of anxiety, depression and trauma symptoms in this patient group.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Nov 2020
Typical duration for all trials
50 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
November 17, 2020
CompletedFirst Submitted
Initial submission to the registry
October 18, 2021
CompletedFirst Posted
Study publicly available on registry
October 25, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 14, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
November 17, 2023
CompletedNovember 28, 2023
November 1, 2023
2.2 years
October 18, 2021
November 21, 2023
Conditions
Outcome Measures
Primary Outcomes (3)
Anxiety
Hospital Anxiety and Depression Scale (HADS) where a score of 0-7= normal, 8-10= borderline abnormal (borderline case), 11-21= abnormal (case).
6 months post intensive care unit (ICU) discharge
Depression
Hospital Anxiety and Depression Scale (HADS) where a score of 0-7= normal, 8-10= borderline abnormal (borderline case), 11-21= abnormal (case).
6 months post ICU discharge
Symptoms of trauma
Impact of Event Scale-6 (IES-6) where the mean score ranges between 0 and 4 and the cut off score is 1.75.
6 months post ICU discharge
Secondary Outcomes (6)
Anxiety
3 and/or 12 months post ICU discharge
Depression
3 and/or 12 months post ICU discharge
Symptoms of trauma
3 and/or 12 months post ICU discharge
Metacognitive beliefs and processes
3, 6 and/or 12 months post ICU discharge
Health-related quality of life
3, 6 and/or 12 months post ICU discharge
- +1 more secondary outcomes
Eligibility Criteria
Intensive care survivors
You may qualify if:
- Adult patients ≥18 years
- Survival to intensive care / high dependency unit discharge following an admission of ≥24 hours
- Treated for COVID-19
You may not qualify if:
- Unable to complete questionnaires
- Unable or unwilling to consent
- Unable to speak, understand or communicate in English
- Patients with diagnosed, pre-existing cognitive impairment (at the time of ICU admission)
- Patients without a fixed abode, at which postal questionnaires might be received, and who have no access to a personal email address.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (50)
Royal Cornwall Hospital
Truro, Cornwall, TR1 3LJ, United Kingdom
Barnsley Hospital
Barnsley, England, S75 2EP, United Kingdom
Basildon Hospital
Basildon, England, SS16 5NL, United Kingdom
Bedford Hospital
Bedford, England, MK42 9DJ, United Kingdom
Royal Blackburn Hospital
Blackburn, England, BB2 3HH, United Kingdom
Pilgrim Hospital
Boston, England, PE21 9QS, United Kingdom
Royal Papworth Hospital
Cambridge, England, CB2 0AY, United Kingdom
Cumberland Infirmary
Carlisle, England, CA2 7HY, United Kingdom
Countess of Chester Hospital
Chester, England, CH2 1UL, United Kingdom
Chesterfield Royal Hospital
Chesterfield, England, S44 5BL, United Kingdom
Colchester Hospital
Colchester, England, CO4 5JL, United Kingdom
Leighton Hospital
Crewe, England, CW1 4QJ, United Kingdom
Wonford Hospital
Exeter, England, EX2 5DW, United Kingdom
Queen Elizabeth Hospital
Gateshead, England, NE9 6SX, United Kingdom
Ipswich Hospital
Ipswich, England, IP4 5PD, United Kingdom
Kingston Hospital
Kingston upon Thames, England, KT2 7QB, United Kingdom
Lincoln County Hospital
Lincoln, England, LN2 5QY, United Kingdom
Royal Liverpool University Hospital
Liverpool, England, L7 8XP, United Kingdom
Aintree University Hospital
Liverpool, England, WD18 0HB, United Kingdom
Lewisham and Greenwich Hospitals
London, England, SE13 6LH, United Kingdom
King's College Hospital NHS Foundation Trust
London, England, SE5 9RS, United Kingdom
Macclesfield District General Hospital
Macclesfield, England, SK10 3BL, United Kingdom
Maidstone Hospital
Maidstone, England, ME16 9QQ, United Kingdom
James Cook University Hospital
Middlesbrough, England, TS4 3BW, United Kingdom
Northumbria Healthcare NHS Foundation Trust
Newcastle upon Tyne, England, NE27 0QJ, United Kingdom
Newcastle upon Tyne Hospitals Foundation Trust
Newcastle upon Tyne, England, NE7 7DN, United Kingdom
Northampton General Hospital
Northampton, England, NN1 5BD, United Kingdom
Nottingham University Hospitals
Nottingham, England, NG5 1PB, United Kingdom
Royal Oldham Hospital
Oldham, England, OL1 2JH, United Kingdom
Derriford Hospital
Plymouth, England, PL6 8DH, United Kingdom
Whiston Hospital
Prescot, England, L35 5DR, United Kingdom
Rotherham General Hospital
Rotherham, England, S60 2UD, United Kingdom
Tunbridge Wells Hospital
Royal Tunbridge Wells, England, TN2 4QJ, United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
Sheffield, England, S10 2JF, United Kingdom
Lister Hospital
Stevenage, England, SG1 4AB, United Kingdom
King's Mill Hospital
Sutton in Ashfield, England, NG17 4JL, United Kingdom
Musgrove Park Hospital
Taunton, England, TA1 5DA, United Kingdom
Pinderfields General Hospital
Wakefield, England, WF1 4DG, United Kingdom
Watford General Hospital
Watford, England, WD18 0HB, United Kingdom
Royal Albert Edward Infirmary
Wigan, England, WN1 2NN, United Kingdom
Ulster Hospital
Belfast, Northern Ireland, BT16 1RH, United Kingdom
Forth Valley Royal Hospital
Larbert, Scotland, FK5 4WR, United Kingdom
University Hospital of Wales
Cardiff, Wales, CF14 4XW, United Kingdom
Royal Glamorgan Hospital
Pont-y-clun, Wales, CF72 8XR, United Kingdom
Morriston Hospital
Swansea, Wales, SA6 6NL, United Kingdom
North Middlesex University Hospital
London, N18 1QX, United Kingdom
Southend University Hospital
London, SS2 6XT, United Kingdom
Manchester Royal Infirmary
Manchester, M13 9WL, United Kingdom
North Manchester General Hospital
Manchester, M8 5RB, United Kingdom
Barking, Havering and Redbridge University Hospitals NHS Trust
Romford, RM7 0AG, United Kingdom
Related Publications (1)
Waite AAC, Johnston BW, Boyle AJ, Cherry MG, Fisher P, Brown SL, Jones C, Williams K, Welters ID. PIM-COVID study: protocol for a multicentre, longitudinal study measuring the psychological impact of surviving an intensive care admission due to COVID-19 on patients in the UK. BMJ Open. 2023 Sep 27;13(9):e071730. doi: 10.1136/bmjopen-2023-071730.
PMID: 37758678DERIVED
Related Links
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Alicia AC Waite
Royal Liverpool University Hospital
- PRINCIPAL INVESTIGATOR
Ingeborg D Welters
University of Liverpool
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER GOV
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Postdoctoral Clinical Research Fellow
Study Record Dates
First Submitted
October 18, 2021
First Posted
October 25, 2021
Study Start
November 17, 2020
Primary Completion
February 14, 2023
Study Completion
November 17, 2023
Last Updated
November 28, 2023
Record last verified: 2023-11