Macintosh Versus GlideScope Versus C-MAC for Double Lumen Endotracheal Intubation

NCT05091281 | Completed

• 1 other identifier: 34776/7/21
• Study Type: interventional
• Target: 105
• Locations: 1 country
• Sites: 1

Brief Summary

The double lumen endotracheal tube (DLT) is the most widely-used device for single lung ventilation in current thoracic anesthesia practice. In recent years, the routine application of the videolaryngoscope for single lumen endotracheal intubation has increased; nevertheless there are few studies of the use of the videolaryngoscope for DLT. The authors wondered whether there were benefits to using the videolaryngoscope for DLT placement in patients with predicted normal airways. Therefore, this study was designed to compare the performances of the GlideScope®, the C-MAC®(D) videolaryngoscope and the Macintosh laryngoscope in DLT intubation.

Conditions

Thoracic

Keywords

Macintosh; laryngoscope; GlideScope; C-MAC; videolaryngoscope; double lumen tube

Outcome Measures

Primary Outcomes (2)

• Double lumen tube insertion times in seconds

  Double lumen tube insertion times by the three types of laryngoscopes were recorded

  2 minutes

• first-pass success rates

  Double lumen tube insertion first-pass success ratesby the three types of laryngoscopes were recorded

  2 minutes

Secondary Outcomes (2)

• Blood pressure measurement in mm Hg

  150 minutes

• Heart rate measurement in beat/minute

  150 minutes

Study Arms (3)

Group I

ACTIVE COMPARATOR

After induction of anesthesia intubation was done by Macintosh laryngoscope

Device: Intubation of the double lumen tube by Macintoch laryngoscope

Group II

ACTIVE COMPARATOR

After induction of anesthesia intubation was done by GlideScope®videolaryngoscope

Device: Intubation of the double lumen tube by Glidescope videolaryngoscope

Group III

ACTIVE COMPARATOR

After induction of anesthesia intubation was done byC-MAC®(D) videolaryngoscope

Device: Intubation of the double lumen tube by C-MAC®(D) videolaryngoscope

Interventions

Intubation of the double lumen tube by Macintoch laryngoscope DEVICE

After induction of anesthesia insertion of the double lumen tube was done by Macintosh laryngoscope

Group I

Intubation of the double lumen tube by Glidescope videolaryngoscope DEVICE

After induction of anesthesia insertion of the double lumen tube was done by GlideScope® videolaryngoscope

Group II

Intubation of the double lumen tube by C-MAC®(D) videolaryngoscope DEVICE

After induction of anesthesia insertion of the double lumen tube was done by C-MAC®(D) videolaryngoscope

Group III

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• ASA I-II
• BMI \< 35 kg/m2
• Mallampati score of 1 or 2

You may not qualify if:

• Patients with risk of gastric aspiration
• Patients with risk of gastric aspiration
• Presence of any predictors of difficult intubation

Sponsors & Collaborators

• Tanta University: lead

Study Sites (1)

Mona Mohamed Mogahed

Tanta, Elgharbia, Egypt

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Masking Details: Before the study, the computerized randomization will be performed and the allocation results will be placed in individual numbered and sealed envelopes. Patients remained blinded about their intubation technique until post-operative assessment was completed.
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate professor

Model Details: Patients randomly assigned into Macintosh group, GlideScope (Verathon Medical, Bothwell, UT, USA) group, or CMAC(D) (Karl Storz GmbHand Co.KG, Tuttlingen, Germany) group. After pre-oxygenation , anesthesia will be induced with intravenous midazolam 0.05 mg. kg- 1 , propofol 1.5 mg. kg- 1 , fentanyl 5 μg. kg- 1 , and rocuronium 0.6 mg. kg- 1 . . The DLT will be inserted with the distal concavity facing anteriorly until the bronchial lumen cuff passed the vocal cords. The stylet will be then removed, and rotation will be performed while tube will be advanced. The left DLT rotated 90° counter-clockwise, and the right DLT will be rotated 90° clockwise to enter the respective mainstem bronchus.

Study Record Dates

• First Submitted: October 1, 2021
• First Posted: October 25, 2021
• Study Start: November 5, 2021
• Primary Completion: January 10, 2022
• Study Completion: January 10, 2022
• Last Updated: January 12, 2022

Record last verified: 2022-01

Locations

EG (1)