The Early Prediction of Sepsis in ICU
1 other identifier
observational
400
1 country
1
Brief Summary
Sepsis is a vital issue in critical care medicine, and early detection and intervention are key to survival. We aimed to establish an early warning system for sepsis based on a data integration platform that can be implemented in the ICU.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started May 2020
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 30, 2020
CompletedFirst Submitted
Initial submission to the registry
October 18, 2021
CompletedFirst Posted
Study publicly available on registry
October 22, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2023
CompletedOctober 22, 2021
October 1, 2021
2.6 years
October 18, 2021
October 19, 2021
Conditions
Outcome Measures
Primary Outcomes (1)
confidence index of sepsis occurrence
sepsis occurrence in five hours
Study Arms (2)
non-sepsis
sepsis
Interventions
Eligibility Criteria
patients that were admitted into the ICU.
You may qualify if:
- Patients who met all of the following criteria were included in the case group:
- At least 14 years old.
- Sepsis onset at least 5 hours after ICU admission.
- Sepsis onset is the first instance since admission to the hospital.
You may not qualify if:
- Patients meeting all of the following criteria were included in the control group:
- At least 14 years old.
- Patients staying in ICU for at least 5 hours and have not had sepsis in this time.
- Patients without ICD-9 codes for sepsis (785·52, 995·91, 995·92).
- SOFA score change is not more than 1 point in an arbitrary continuous 72 hours in the ICU stay.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Ruijin Hospitallead
Study Sites (1)
ICU, Ruijin Hospital
Shanghai, Shanghai Municipality, 200025, China
Related Publications (1)
Chen Q, Li R, Lin C, Lai C, Chen D, Qu H, Huang Y, Lu W, Tang Y, Li L. Transferability and interpretability of the sepsis prediction models in the intensive care unit. BMC Med Inform Decis Mak. 2022 Dec 29;22(1):343. doi: 10.1186/s12911-022-02090-3.
PMID: 36581881DERIVED
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- chief physician
Study Record Dates
First Submitted
October 18, 2021
First Posted
October 22, 2021
Study Start
May 30, 2020
Primary Completion
December 31, 2022
Study Completion
December 31, 2023
Last Updated
October 22, 2021
Record last verified: 2021-10