NCT05084794

Brief Summary

This study aims prospective randomized comparison of mid-term clinical outcomes of middle-sized posterior malleolus fractures with and without internal fixation.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Oct 2015

Longer than P75 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2015

Completed
4.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 31, 2019

Completed
1.9 years until next milestone

First Submitted

Initial submission to the registry

October 8, 2021

Completed
12 days until next milestone

First Posted

Study publicly available on registry

October 20, 2021

Completed
11 days until next milestone

Study Completion

Last participant's last visit for all outcomes

October 31, 2021

Completed
Last Updated

May 26, 2022

Status Verified

May 1, 2022

Enrollment Period

4.1 years

First QC Date

October 8, 2021

Last Update Submit

May 19, 2022

Conditions

Keywords

anklefractureposteriormalleolusfixation

Outcome Measures

Primary Outcomes (3)

  • Short Musculoskeletal Function Assessment (SMFA) Questionnaire

    Functional outcome score between 0 and 100. Higher score indicates a worse function.

    2 year

  • Kellgren-Lawrence grading system for osteoarthritis

    Grade of ankle osteroarthritis. Score between 0 to 4. Higher score indicates worse joint cartilage.

    2 year

  • American Orhopaedic Foot and Ankle Score (AOFAS) Score

    Functional outcome score between 0 and 100. Higher score indicates better function.

    5 year

Study Arms (2)

Non-fixated

NO INTERVENTION

Posterior malleolus fractures won't be fixated.

Fixated

EXPERIMENTAL

Posterior malleolus fractures will be fixated with either plate or screws.

Procedure: Internal fixation

Interventions

Fixation of posterior malleolus with either plate or screws.

Fixated

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients who were operated for ankle fractures, including posterior malleolar fracture between 10-25% of the joint surface. Two to five years of follow-up with functional and radiological outcome.

You may not qualify if:

  • Posterior malleolar fractures accompanied by severe soft tissue damage after high-energy injury will not be included in the study. Written consent will be obtained from all participants, patients who do not give consent or refuse to participate will not be included in the study. Patients who left the study voluntarily will not be included in the statistics. Patients with additional joint disorders, previous surgery or previous history of ankle complaint will not be included.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Ankle FracturesFractures, Bone

Interventions

Fracture Fixation, Internal

Condition Hierarchy (Ancestors)

Wounds and InjuriesAnkle InjuriesLeg Injuries

Intervention Hierarchy (Ancestors)

Fracture FixationOrthopedic ProceduresTherapeuticsSurgical Procedures, Operative

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

October 8, 2021

First Posted

October 20, 2021

Study Start

October 1, 2015

Primary Completion

October 31, 2019

Study Completion

October 31, 2021

Last Updated

May 26, 2022

Record last verified: 2022-05

Data Sharing

IPD Sharing
Will not share