Burden of Care of Long COVID Patients After Hospital Discharge
BLOC
BLOC
Sponsor study identifier
observational
68,822
1 country
1
Study Start
January 1, 2022
Actual (reported)Primary Completion
July 12, 2022
Actual (reported)Study Completion
August 10, 2022
Actual (reported)Since March 2020, 3.5 million people have been infected with SARS-COV2 in France, and about 250 000 patients have been hospitalized and successfully discharged. In a majority of cases, the evolution of the disease is favourable, but both hospitalized or patients with a mild form of the disease may present so called "Long-COVID" syndrome - a patient-created term which describes the effects of COVID-19 that continue for weeks or months beyond the initial symptoms. There is thus an urgent need to evaluate the long-term medical resource utilisation (MRU) and health care burden incurred by patients with Long-COVID, as well as risk factors for Long-COVID. We will use the SNDS database to extract and analyze the data relevant to the project objectives. Indeed, the SNDS database is the French NHS database providing individual anonymous information of primary and secondary care linked at individual level (data from PMSI, the French DRG-based medical information system). It currently covers more than 98% of the French population. For the first time, our study will provide an estimation of MRU and associated costs of hospitalized COVID-19 patients. It will also provide an estimation of the rate of long COVID forms developed by hospitalized COVID patients, as well as detailed MRU and costs incurred by long COVID patients compared to patients with non-long COVID-19.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
August 10, 2022
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
October 8, 2021
Actual (reported)October 11, 2021
Actual (reported)January 1, 2022
Actual (reported)July 12, 2022
Actual (reported)August 10, 2022
Actual (reported)MRU (medical resource use )
The primary outcome will be the description of MRU and related costs during the 6 months following the discharge date, i.e.: * medications, * medical, including chronic pain structure consultation/admission, * emergency room visits * paramedical visits (e.g. nurse visits, physiotherapist, psychologist) * specific therapies including pain management, * medical procedures, biological acts * new hospitalizations (for any reason), * sick leaves, * transportation
6 months following the discharge date
Predictive variables for "long-COVID"
up to 1 year before the hospitalisation date
Patterns of long-COVID healthcare consumption
6 months following the discharge date
COVID-19 patients discharged from all French hospitals from 01 February to 30 June 2020
this cohort will include patients with at least 4 weeks of claims and specific health care use after hospital admission from the initial cohort (COVID-19 patients) According to the Haute Autorité de Santé (HAS), the most frequent symptoms in the context of long COVID are the following : * Major fatigue * Dyspnoea, cough * Chest pain, often tightness type, palpitations * Problems with concentration and memory, lack of words * Headache, paraesthesia, burning sensation * Disorders of smell, taste, tinnitus, dizziness, odynophagia * Muscle, tendon or joint pain * Sleep disorders (especially insomnia) * Irritability, anxiety * Abdominal pain, nausea, diarrhea, decrease or loss of appetite * Pruritus, urticaria, pseudo-frostbite * Fever, chills
all other patients from the initial cohort (COVID-19 patients )
Patients who contracted a COVID19 required hospitalisation
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Adult COVID-19 patients discharged from all French hospitals from 01 February to 30 June 2020
Hopital de la Croix Rousse - Hospices Civils de Lyon
Lyon, 69004, France
Dziadzko M, Belhassen M, Van Ganse E, Heritier F, Berard M, Marant-Micallef C, Aubrun F. Health Care Resource Use and Total Mortality After Hospital Admission for Severe COVID-19 Infections During the Initial Pandemic Wave in France: Descriptive Study. JMIR Public Health Surveill. 2024 Sep 11;10:e56398. doi: 10.2196/56398.
Mikhail DZIADZKO, MD, PhD
Hospices Civils de Lyon
Frederic Aubrun, MD, PhD
Hospices Civils de Lyon
Eric VAN-GANSE, MD, PhD
Hospices Civils de Lyon
Pierre ALBALADEJO, MD, PhD
CHU Grenoble Alpes
68,822 participants (actual enrollment reported by the registry).
First Submitted
October 8, 2021
First Posted
October 11, 2021
Study Start
January 1, 2022
Actual (reported)Geriatric Care for Older People Hospitalised for COVID-19
Contact the study team to confirm eligibility.
Florence ADER, MD, PhD
Hospices Civils de Lyon
Valeria MARTINEZ, MD, PhD
Hôpital Raymond-Poincaré - APHP
Claire MARANT-MICALLEF, PharmD, MPH
PELyon
Manon BELHASSEN, MD, PhD
PELyon
Fabrice HERITIER, MD
Hospices Civils de Lyon
Primary Completion
July 12, 2022
Actual (reported)Study Completion
August 10, 2022
Actual (reported)Last Updated
October 2, 2024
Record last verified: 2024-09
individual participant data are protected by the French legislation and are not shared
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: