Acute Kidney Injury as a Risk Factor for Myocardial Injury After Non Cardiac Surgery

NCT05068167 | Completed

• 1 other identifier: ACI after non cardiac surgery
• Study Type: observational
• Target: 240
• Locations: 1 country
• Sites: 1

Brief Summary

The incidence of acute kidney injury (AKI) postoperatively has been identified to be 21.6% in adults and 18.3% in hospitalized individuals. Surgery-related AKI is a severe complication that is related not only to short-term complications as increases in mortality rate and development of cardiac complications but also with complications on long term, such as development of chronic kidney disease. A better understanding of the mechanism of this hypthesis will lead to better management of this complication.

Conditions

Acute Kidney Injury (AKI)

Outcome Measures

Primary Outcomes (1)

• Creatinine level

  Creatinine twice the baseline and urine output of fewer than 0.5 ml/kg per hour for 12 hours

  every 12 hours

Interventions

Kidney function test DIAGNOSTIC_TEST

Creatinine twice the baseline and urine output of fewer than 0.5 ml/kg per hour for 12 hours

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patients who were candidates for major surgery in the Cancer Institute of South Egypt, Assiut University, Egypt. Patients excluded from this study were patients with chronic cardiac diseases (myocardial ischemia, heart failure, Active severe infection, pregnancy, chronic kidney disease, DM, and advanced malignancy on chemotherapy or radiotherapy.

You may qualify if:

• patients who were candidates for major non cardiac surgery

You may not qualify if:

• chronic cardiac diseases (myocardial ischemia, heart failure), Active severe infection, pregnancy, chronic kidney disease

Sponsors & Collaborators

• South Egypt Cancer Institute: lead

Study Sites (1)

Alaa Ali Elzohry

Asyut, +2071516, Egypt

Location

MeSH Terms

Conditions

Acute Kidney Injury

Interventions

Kidney Function Tests

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases

Intervention Hierarchy (Ancestors)

Diagnostic Techniques, Urological; Diagnostic Techniques and Procedures; Diagnosis

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of Anesthesia, ICU and Pain Relief, South Egypt Cancer Institute, Assiut University, Egypt

Study Record Dates

• First Submitted: September 24, 2021
• First Posted: October 5, 2021
• Study Start: March 1, 2019
• Primary Completion: August 30, 2020
• Study Completion: September 30, 2020
• Last Updated: October 5, 2021

Record last verified: 2021-09

Locations

EG (1)