Effects of Antibiotic Therapy on the Short and Long-term Results of Periodontitis Treatments

NCT05065034 | Unknown

• 1 other identifier: 8333
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

Antibiotics are currently used in periodontology to specifically target the most pathogenic bacteria in subgingival biofilms and to improve treatments. The multiplicity of protocols / dosages tested and the variability of the results did not make it possible to reach an international consensus on antibiotic therapy and its cost / benefit ratio, in particular with regard to the significant side effects of taking antibiotics (resistance bacterial). The care environment as well as the clinical, biological and microbiological parameters can strongly influence the results in usual treatment.

Conditions

Periodontitis, Adult

Keywords

Periodontitis; Inflammatory diseases; Periodontal; Teeth; Aesthetic morbidity; Cardiovascular risk; Supragingival; Subgingival; Biofilms; Prosthetic restorations

Outcome Measures

Primary Outcomes (1)

• A retrospective study of the use of antibiotic therapy on the short and long-term results of periodontitis treatments

  Files analysed retrospectively from January 01, 2012 to July 07, 2021 will be examined]

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patient adult treated for periodontitis

You may qualify if:

• Patient over 18 years old
• Patient treated for periodontitis between 01/01/2012 and 07/31/2021
• Patient whose medical and periodontal file contains all the elements necessary for data analysis
• Subject not having expressed, after information, his opposition to the reuse of his medical data for the purposes of this research.

You may not qualify if:

• Patient who expressed his opposition to participating in the study
• Patient without periodontitis
• Patient smoking more than 10 cigarettes / day
• Patient presenting a dilapidated oral state (untreated caries, unrestored teeth), oral infectious foci whose management requires antibiotic treatment during the initial treatment
• Impossibility of giving the subject informed information
• Subject under safeguard of justice
• Subject under guardianship or guardianship

Sponsors & Collaborators

• University Hospital, Strasbourg, France: lead

Study Sites (1)

Service de Médecine et de Chirurgie Bucco-Dentaires - Hôpitaux Universitaires de Strasbourg

Strasbourg, 67091, France

RECRUITING

MeSH Terms

Conditions

Chronic Periodontitis; Periodontitis

Condition Hierarchy (Ancestors)

Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Jean-Luc DAVIDEAU, MD, PhD

  Service de Médecine et de Chirurgie Bucco-Dentaires - Hôpitaux Universitaires de Strasbourg

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Jean-Luc DAVIDEAU, MD, PhD

CONTACT

33 3 88 11 69 47; jean.luc.davideau@chru-strasbourg.fr

Saïd CHAYER, PhD, HDR

CONTACT

said.chayer@chru-strasbourg.fr

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 29, 2021
• First Posted: October 1, 2021
• Study Start: September 29, 2021
• Primary Completion: June 25, 2023
• Study Completion: June 25, 2023
• Last Updated: October 12, 2021

Record last verified: 2021-09

Locations

FR (1)