NCT05062252

Brief Summary

The purpose of this study is to demonstrate safety and efficacy of the Mirror Medacta Shoulder System in total shoulder arthroplasty.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
20mo left

Started Jan 2022

Longer than P75 for not_applicable

Geographic Reach
1 country

2 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress72%
Jan 2022Dec 2027

First Submitted

Initial submission to the registry

September 21, 2021

Completed
9 days until next milestone

First Posted

Study publicly available on registry

September 30, 2021

Completed
3 months until next milestone

Study Start

First participant enrolled

January 5, 2022

Completed
5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 30, 2026

Expected
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 30, 2027

Last Updated

May 8, 2025

Status Verified

May 1, 2025

Enrollment Period

5 years

First QC Date

September 21, 2021

Last Update Submit

May 7, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Oxford Shoulder Score

    0 (worst) - 48 (best)

    12 months

Secondary Outcomes (5)

  • Device Success Rate

    24 months

  • Oxford Shoulder Score

    24 months

  • Constant score

    24 months

  • Subjective Shoulder Value

    24 months

  • Device parameters

    24 months

Study Arms (2)

Mirror group

EXPERIMENTAL

Mirror Medacta Shoulder System

Device: Mirror Medacta Shoulder System

Historical Control group

ACTIVE COMPARATOR

Total shoulder arthroplasty system

Device: Medacta Shoulder System

Interventions

Anatomic total shoulder arthroplasty system

Mirror group

Anatomic total shoulder arthroplasty system - standard configuration

Historical Control group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age ≥ 18 yr
  • Clinical indication for anatomic primary total shoulder replacement due to osteoarthritis and/or posttraumatic arthritis
  • Willingness and ability to comply with study protocol

You may not qualify if:

  • Medical condition or balance impairment that could lead to falls
  • Prior rotator cuff surgery
  • Cuff tear arthropathy/insufficient rotator cuff
  • Insufficient bone quality which may affect the stability of the implant
  • Neuromuscular compromise of shoulder or other disabilities affecting the maximum functional outcomes
  • Weight bearing shoulder due to wheel chair, crutches, rollator at the time of operation
  • Active metastatic or neoplastic disease at the shoulder joint
  • Chemotherapy treatment/radiotherapy within 6 mo before surgery
  • \>5 mg/day of corticosteroids, excluding inhalers, within 3 years before surgery
  • Pregnancy or plan to become pregnant during study period
  • Inability to understand study or a history of noncompliance with medical advice
  • Alcohol or drug abuse
  • Current enrollment in any clinical research study that might interfere with this study
  • Metal allergies or sensitivity.
  • Previous or current infection at or near the site of implantation.
  • +3 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Lindenhofgruppe AG - Orthopädie Sonnenhof

Bern, 3006, Switzerland

RECRUITING

Klinik für Orthopädische Chirurgie und Traumatologie des Bewegungsapparates, Kantonsspital St.Gallen

Sankt Gallen, 9007, Switzerland

RECRUITING

Study Officials

  • Matthias A Zumstein, Prof Dr. med

    Lindenhofgruppe AG (Bern)

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Marco Viganò, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 21, 2021

First Posted

September 30, 2021

Study Start

January 5, 2022

Primary Completion (Estimated)

December 30, 2026

Study Completion (Estimated)

December 30, 2027

Last Updated

May 8, 2025

Record last verified: 2025-05

Data Sharing

IPD Sharing
Will not share

Locations