Vitamin D3 - Omega3 - Home Exercise - HeALTHy Aging and Longevity Cohort
DO-HEALTH-C
1 other identifier
observational
534
1 country
1
Brief Summary
The DO-HEALTH trial will be extended into the cohort including the collection on life style factors such as diet, quality of life and physical activity, as well as health-related data on co-morbid conditions as well as a standardized assessment of multiple organ functions, physical, cognitive and mental function using surveys and standardized health assessments.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Nov 2019
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
November 26, 2019
CompletedFirst Submitted
Initial submission to the registry
September 20, 2021
CompletedFirst Posted
Study publicly available on registry
September 30, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2023
CompletedDecember 6, 2022
December 1, 2022
4.1 years
September 20, 2021
December 2, 2022
Conditions
Outcome Measures
Primary Outcomes (5)
Incidence of functional decline
assessed by short physical performance test battery
24 months
Incidence of injurious falls
assessed by fall questionnaire at each visit
24 months
Incidence of high blood pressure
Standardized blood pressure assessment in sitting position
24 months
Incidence of cognitive decline
assessed by Montreal Cognitive Assessment (MoCA)
24 months
Incidence of infections
assessed by infection questionnaire at each visit
24 months
Secondary Outcomes (47)
Incidence and prevalence of frailty
24 months
Incidence and prevalence of impaired mobility
24 months
Incidence and prevalence of functional dependency
24 months
Incidence and prevalence of anemia or iron deficiency
24 months
Incidence and prevalence of any cardiovascular disease
24 months
- +42 more secondary outcomes
Eligibility Criteria
The DO-HEALTH Cohort includes the population of the former DO-HEALTH clinical trial (NCT01745263)
You may qualify if:
- Former participation in the DO-HEALTH clinical trial study
You may not qualify if:
- Inability or unwillingness to give written informed consent
- Medical condition that would make the results of the tests/assessments unreliable and/or would put too much burden to the participant, and/or leads to safety concerns.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Centre on Aging and Mobility, University of Zurich, City Hospital Zurich
Zurich, Switzerland
Biospecimen
whole blood, serum, plasma, urine
Study Officials
- PRINCIPAL INVESTIGATOR
Heike Bischoff-Ferrari, Prof. Dr. med. DrPH
University of Zurich
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Prof. Dr. med. DrPH
Study Record Dates
First Submitted
September 20, 2021
First Posted
September 30, 2021
Study Start
November 26, 2019
Primary Completion
December 31, 2023
Study Completion
December 31, 2023
Last Updated
December 6, 2022
Record last verified: 2022-12
Data Sharing
- IPD Sharing
- Will not share