Trials Sponsors Conditions Drugs Pricing

NCT05061784

Completed

Routine Transcervical Thymectomy in MEN-1 Patients

National University Health System, Singapore Source

Conditions

Multiple Endocrine Neoplasia Type 1 (MEN-1)Thymic Carcinoid

Keywords

Routine transcervical thymectomy

Outcome Measures

Primary Outcomes (1)

Incidence of thyme carcinoid
Retrospective review of published studies
The timeframe will be from date of transcervical thymectomy until the date of documented diagnosis of diagnosis of thymic NET; progression of disease or date of death from any cause, whichever came first, assessed up to 100 months.

Study Arms (1)

MEN-1 patients who underwent routine thymectomy during parathyroidecotmy

A case series was built after review of available literature by searching four databases (PubMed, Embase, Medline and Cochrane Library) for observational studies or case reports on routine prophylactic TCT for MEN-1 and the development of thymic carcinoids.

Procedure: Routine thymectomy, which has been performed

Interventions

Routine thymectomy, which has been performedProcedure

There is no intervention

MEN-1 patients who underwent routine thymectomy during parathyroidecotmy

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years+

Sexall

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

We accepted randomized controlled trials or observational studies that included patients of any age who underwent a routine TCT in the setting for MEN-1, published as full-length articles in peer-reviewed journals, which mentioned data on thymic carcinoid tumours.

You may qualify if:

Studies including MEN-1 patients who underwent a routine thymectomy during parathyoidectomy

Sponsors & Collaborators

National University Health System, Singapore
Otherlead

Study Sites (1)

National University Hospital

Singapore, Singapore

MeSH Terms

Conditions

Multiple Endocrine Neoplasia Type 1

Condition Hierarchy (Ancestors)

Multiple Endocrine NeoplasiaEndocrine Gland NeoplasmsNeoplasms by SiteNeoplasmsNeoplasms, Multiple PrimaryNeoplastic Syndromes, HereditaryGenetic Diseases, InbornCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesEndocrine System Diseases

Enrollment

7 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: CASE ONLY
Time Perspective: RETROSPECTIVE
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Assistant Professor and Head & Senior Consultant

Study Record Dates

First Submitted

September 2, 2021

First Posted

September 30, 2021

Study Start

July 14, 2021

Actual (reported)

Routine Transcervical Thymectomy in MEN-1 Patients

Routine Transcervical Thymectomy in MEN-1 Patients

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Study Arms (1)

MEN-1 patients who underwent routine thymectomy during parathyroidecotmy

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Study Arms (1)

MEN-1 patients who underwent routine thymectomy during parathyroidecotmy

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations