NCT05061602

Brief Summary

In this study, an attempt has been made to analyze the changes in soft tissue biomechanical properties of plantar surface in diabetes. The second aim of this study was to explore the relationships between fear of falling, physical performance, and plantar stiffness in patients with diabetes.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Sep 2021

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 20, 2021

Completed
Same day until next milestone

Study Start

First participant enrolled

September 20, 2021

Completed
9 days until next milestone

First Posted

Study publicly available on registry

September 29, 2021

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 30, 2022

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

July 10, 2022

Completed
Last Updated

July 27, 2023

Status Verified

July 1, 2023

Enrollment Period

8 months

First QC Date

September 20, 2021

Last Update Submit

July 26, 2023

Conditions

Keywords

Plantar FasciaStiffnessDiabetes mellitusFear

Outcome Measures

Primary Outcomes (1)

  • Biomechanical and Viscoelastic Properties

    The biomechanical and viscoelastic properties of the plantar fascia will be measured with MyotonPRO device. The MyotonPRO (Tallin, Estonia) is a portable hand-held myotonometer. This device is non-invasive and provides a quantitative assessment of a muscle's viscoelastic properties. These properties are characterized by different parameters such as tone, elasticity, and stiffness. The MyotonPRO applies a short-intensity mechanical impulse on the skin overlying the muscle or facia. The tissue's response then generates a signal that is recorded, and an internal software program produces an acceleration graph.

    Day 1.

Secondary Outcomes (2)

  • Fear of Falling

    Day 1.

  • Lower Limb Function

    Day 1.

Study Arms (2)

Diabetic Group

The patients were included if they were of 18 years or older, with a diagnosis of diabetes mellitus for more than three years.

Diagnostic Test: Evaluation of biomechanics and viscoelastic properties of plantar fascia

NonDiabetic Group

The healthy age-matched control group was included.

Diagnostic Test: Evaluation of biomechanics and viscoelastic properties of plantar fascia

Interventions

The biomechanical and viscoelastic properties of the plantar fascia will be measured with the MyotonPRO device.

Also known as: Falls Efficacy Scale
Diabetic GroupNonDiabetic Group

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients with a diagnosis of diabetes mellitus for more than three years or individuals without a history of diabetes mellitus affirmed by a normal range of fasting blood sugar and hemoglobin A1C levels.

You may qualify if:

  • Diagnosed with diabetes mellitus for more than three years
  • Individuals without a history of diabetes mellitus affirmed by a normal range of fasting blood sugar and hemoglobin A1C levels.
  • Age≥18 years

You may not qualify if:

  • History of central nervous system conditions
  • No visual and vestibular impairments
  • Amputation of the lower limb
  • History of fracture
  • Surgery of lumbar and lower limb
  • Having pain resulting in movement difficulty

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Okan University Hospital

Istanbul, 34959, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Diabetes Mellitus

Condition Hierarchy (Ancestors)

Glucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Target Duration
1 Day
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Sponsor-Investigator

Study Record Dates

First Submitted

September 20, 2021

First Posted

September 29, 2021

Study Start

September 20, 2021

Primary Completion

May 30, 2022

Study Completion

July 10, 2022

Last Updated

July 27, 2023

Record last verified: 2023-07

Locations