Comparison of Aerobic, Resistance, and Combined Training in Overweight/Obese Hypertensive Adults

NCT05061173 | Completed DMC

• 1 other identifier: REC/01083 Sidra Asghar
• Study Type: interventional
• Target: 63
• Locations: 1 country
• Sites: 1

Brief Summary

To compare the effects of aerobic, resistance and combined training in hypertensive obese patients

Conditions

Obese; Hypertension

Keywords

Aerobic Exercise; Resistive exercise; Combined Aerobic and Resistive Exercise

Outcome Measures

Primary Outcomes (5)

• Systolic and diastolic blood pressure

  Changes from the Baseline, Blood pressure is measured through sphygmomanometer

  6 weeks

• Body Mass Index (BMI)

  Changes from the Baseline, Body mass index (BMI) will be calculated as weight (kg)/height (m2). Below 18.5 Underweight 18.5 - 24.9 Healthy Weight 25.0 - 29.9 Overweight 30.0 and Above Obesity

  6 Week

• Change in blood lipid profile

  Change in plasma total cholesterol, high density lipoproteins cholesterol (HDL), and low density lipoproteins cholesterol (LDL) after each treatment.

  6 Week

• Step Count

  Pedometer is a valid self-report measure of physical activity. Pedometer is used to count the average daily steps. Change from the baseline to 6 week will be compared.

  6 week

• Waist circumference

  Waist circumference will be measured for abdominal or central fat mass. It is measured in cm at the middle distance between the last floating rib and the iliac crest using a retractable ergonomic measuring tape. Change from the baseline to 6 week will be compared.

  6 week

Study Arms (3)

Aerobic exercise training Group

EXPERIMENTAL

Other: Aerobic exercise training Group

Resistance Exercise Training Group

EXPERIMENTAL

Other: Resistance Exercise Training Group

Combined Exercise Training Group

EXPERIMENTAL

Other: Combined Exercise Training Group

Interventions

Aerobic exercise training Group OTHER

Aerobic Exercise includes Treadmill walking At Week 1-2, intensity of 40-45% Heart rate maximum (HR max), 3 days/week, for 30 minutes At Week 3-4, intensity of 45-50% HR max, 3 days /week, for 30 minutes At Week 5-6, intensity of 50-60% HR max 3 days per week, for 30 minutes

Aerobic exercise training Group

Resistance Exercise Training Group OTHER

Resistive Exercises includes (a) Leg press b) Quadriceps extension c) Bicep curl d) Hip abduction. At Week 1-2, 10 repetitions 1 set, 3 days/week, for 30 minutes At Week 3-4, 2 sets of 10 repetitions, 3 times /week for 30 minutes At week 5-6, 2 sets of 10 repetitions with 5 sec hold 3 times per week for 30 minutes

Resistance Exercise Training Group

Combined Exercise Training Group OTHER

Combined Exercise training includes \[Aerobic: Treadmill walking + Resistive Training: a) Leg press b) Quadriceps extension c) Bicep curl d) Hip abduction\] Time will be reduced to 15 minutes for both trainings in respective weeks. Aerobic Exercise includes Treadmill walking At Week 1-2, intensity of 40-45% Heart rate maximum (HR max), 3 days/week, for 15 minutes At Week 3-4, intensity of 45-50% HR max, 3 days /week, for 15 minutes At Week 5-6, intensity of 50-60% HR max 3 days per week, for 15 minutes Resistive Exercises At Week 1-2, 10 repetitions 1 set, 3 days/week, for 15 minutes At Week 3-4, 2 sets of 10 repetitions, 3 times /week for 15 minutes At week 5-6, 2 sets of 10 repetitions with 5 sec hold 3 times per week for 15 minutes

Combined Exercise Training Group

Eligibility Criteria

• Age: 40 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Hypertensive with BP greater than 140/90 mmHg
• Overweight and obese adults with BMI (25-40)
• Physically inactive from past 6 months assessed with pedometer. Those with step count of less than 7000 will be included
• To be able to exercise (6MWT),t hose who completed the test without any symptom

You may not qualify if:

• Any active systemic illness that restricts exercise
• People doing exercise on regular basis
• Any cardiopulmonary , metabolic and neurological illness

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

District Headquarter Hospital - kotli

Kotli, Azad Jamu Kashmir, 11100, Pakistan

Location

MeSH Terms

Conditions

Obesity; Hypertension

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Muhammad Iqbal Tariq, MSCPPT

  Riphah International University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 18, 2021
• First Posted: September 29, 2021
• Study Start: September 10, 2021
• Primary Completion: August 30, 2022
• Study Completion: August 30, 2022
• Last Updated: October 24, 2022

Record last verified: 2022-10

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)