NCT05060393

Brief Summary

The presented randomized-controled study aim to assess the use of internet-based mindfulness intervention via mobile application for 30 days in patients with Major Depressive Disorder (MDD)

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
140

participants targeted

Target at P50-P75 for not_applicable depression

Timeline
Completed

Started May 2021

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2021

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

September 8, 2021

Completed
21 days until next milestone

First Posted

Study publicly available on registry

September 29, 2021

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2022

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2023

Completed
Last Updated

September 29, 2021

Status Verified

September 1, 2021

Enrollment Period

1.4 years

First QC Date

September 8, 2021

Last Update Submit

September 17, 2021

Conditions

Outcome Measures

Primary Outcomes (2)

  • Change from baseline self reported Depression Severity

    Beck Depression Inventory

    30 days

  • Change from Baseline Depression Severity

    Hamilton Depression Rating Scale

    30 days

Secondary Outcomes (6)

  • Change from baseline heart rate

    30 days

  • Change from baseline blood pressure

    30 days

  • Change from baseline respiratory rate

    30 days

  • Change from baseline tobacco consumption

    30 days

  • Change from baseline alcohol consumption

    30 days

  • +1 more secondary outcomes

Study Arms (2)

Intervention group

EXPERIMENTAL

Daily use of mindfulness-based mobile application for 30 days.

Behavioral: Mindfulness-based cognitive therapy

Control group

NO INTERVENTION

Treatment as usual

Interventions

Mobile application, mindfulness-based therapy

Intervention group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Depression, current ill

You may not qualify if:

  • acute alcohol- and drug dependency, schizophrenia or psychotic disorder, severe somatic illnes, not having smartphone or not willing to use mobile application

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Jan Sarlon

Basel, Switzerland

RECRUITING

Related Publications (1)

  • Sarlon J, Doll JPK, Schmassmann A, Brand S, Ferreira N, Muehlhauser M, Urech-Meyer S, Schweinfurth N, Lang UE, Bruehl AB. Effectiveness of a Mindfulness-Based Mobile Application for the Treatment of Depression in Ambulatory Care: Protocol for a Randomized Controlled Trial. JMIR Res Protoc. 2022 Mar 31;11(3):e33423. doi: 10.2196/33423.

MeSH Terms

Conditions

Depression

Interventions

Mindfulness-Based Cognitive Therapy

Condition Hierarchy (Ancestors)

Behavioral SymptomsBehavior

Intervention Hierarchy (Ancestors)

MindfulnessCognitive Behavioral TherapyBehavior TherapyPsychotherapyBehavioral Disciplines and Activities

Study Officials

  • Jan Sarlon

    University of Basel

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

September 8, 2021

First Posted

September 29, 2021

Study Start

May 1, 2021

Primary Completion

October 1, 2022

Study Completion

January 1, 2023

Last Updated

September 29, 2021

Record last verified: 2021-09

Data Sharing

IPD Sharing
Will share

All of the individual participant data collected during the trial will be shared, after deidentification.

Shared Documents
STUDY PROTOCOL, ICF
Time Frame
Immediately following publication and ending 5 years following article publication.
Access Criteria
Researchers who provide a methodologically sound proposal.

Locations