Realistic Computational Electrophysiology Simulations for the Targetted Treatment of Atrial Fibrillation

You may not qualify if:

• Any clinical contra-indication to ablation
• Any disease limiting life expectancy to \< 1year
• Contra-indication to MRI including renal dysfunction (eGFR\<30ml/min)
• Potential participant currently pregnant or breast feeding
• Prior ablation, cardiac surgery or presence of any prosthetic valves
• Myocardial infarction or percutaneous coronary intervention within 3 months preceding consent date
• Hypertrophic cardiomyopathy or other inherited cardiac condition
• Presence / likely implant of any pacemaker, cardiac resynchronization therapy device or implantable defibrillator within 1 year
• Enrolment in an existing interventional atrial fibrillation study which alters treatment or follow-up.
• Use of amiodarone for any indication within 6 months prior to the planned ablation procedure
• Use of any anti-arrhythmic drug for an arrhythmia indication other than atrial fibrillation
• Prior documented cavotricuspid isthmus dependent right atrial flutter and planned cavotricuspid isthmus ablation to be performed at the time of atrial fibrillation ablation
• Unable to understand verbal or written explanations given in English or German as appropriate.