OCTA Insights in CNVM, Morphological Characteristics and Correlation With Structural OCT.

NCT05055973 | Unknown

• 1 other identifier: OCTAIICNMMCACWSOCT
• Study Type: observational
• Target: 80
• Locations: 0 countries
• Sites: N/A

Brief Summary

To suggest a novel classification of choroidal neovascular membrane based on optical coherence tomography angiography and to correlate morphological characteristics based on optical coherence tomography with clinical criteria of disease activity.

Conditions

Choroidal Neovascularization

Outcome Measures

Primary Outcomes (1)

• Morphological characters of choroidal neovascular membrane

  To describe morphological criteria of choroidal neovascular membrane using optical coherence tomography angiography (OCTA).

  One year

Secondary Outcomes (1)

• Correlation between morphological characters of choroidal neovascular membrane and disease activity

  One year

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All patients with choroidal neovascular membrane, naive or previously treated.

You may qualify if:

• Patients with all types of CNV, previously treated or naïve.

You may not qualify if:

• The presence of prominent media opacity.
• Significant cataract.
• Poor fixation.
• Any other factor that interferes with obtaining good-quality OCT/OCTA images.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (4)

• Corvi F, Cozzi M, Barbolini E, Nizza D, Belotti M, Staurenghi G, Giani A. COMPARISON BETWEEN SEVERAL OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY DEVICES AND INDOCYANINE GREEN ANGIOGRAPHY OF CHOROIDAL NEOVASCULARIZATION. Retina. 2020 May;40(5):873-880. doi: 10.1097/IAE.0000000000002471.

  PMID: 30807517 RESULT

• Parravano M, Querques L, Scarinci F, Giorno P, De Geronimo D, Gattegna R, Varano M, Bandello F, Querques G. Optical coherence tomography angiography in treated type 2 neovascularization undergoing monthly anti-VEGF treatment. Acta Ophthalmol. 2017 Aug;95(5):e425-e426. doi: 10.1111/aos.13180. Epub 2016 Aug 6. No abstract available.

  PMID: 27496070 RESULT

• Grossniklaus HE, Green WR. Choroidal neovascularization. Am J Ophthalmol. 2004 Mar;137(3):496-503. doi: 10.1016/j.ajo.2003.09.042.

  PMID: 15013874 RESULT

• Querques G, Corvi F, Querques L, Souied EH, Bandello F. Optical Coherence Tomography Angiography of Choroidal Neovascularization Secondary to Pathologic Myopia. Dev Ophthalmol. 2016;56:101-6. doi: 10.1159/000442800. Epub 2016 Mar 15.

  PMID: 27023343 RESULT

MeSH Terms

Conditions

Choroidal Neovascularization

Condition Hierarchy (Ancestors)

Choroid Diseases; Uveal Diseases; Eye Diseases; Neovascularization, Pathologic; Metaplasia; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Samir Y Saleh, PhD

  Assiut University

  STUDY CHAIR

Central Study Contacts

Samir Y Saleh, PhD

CONTACT

01003304320; samir.abouelail@med.aun.edu.eg

Dalia M Elsebety, PhD

CONTACT

01223212962; drdalia@aun.edu.eg

Study Design

• Study Type: observational
• Observational Model: CASE CROSSOVER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principle Investigator

Study Record Dates

• First Submitted: September 12, 2021
• First Posted: September 24, 2021
• Study Start: October 1, 2021
• Primary Completion: October 1, 2022
• Study Completion: December 1, 2022
• Last Updated: September 24, 2021

Record last verified: 2021-09

Data Sharing

• IPD Sharing: Will not share