Postoperative Residual Curarization in Elderly Patients in Post-anesthesia Care Unit

NCT05051371 | Unknown

• 1 other identifier: E1-21-1912
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

In this study, we aimed to determine the knowledge levels and approaches of anesthesiologists working in our clinic about postoperative residual curarization(PORC) in elderly patients with a questionnaire. In addition, we aimed to determine the incidence of PORC and factors associated with PORC in the recovery unit in elderly patients over 65 years of age who underwent surgery under general anesthesia using muscle relaxants with a prospective observational study.

Conditions

Postoperative Residual Curarization; Geriatrics

Keywords

Postoperative residual curarization; Geriatrics; Train of four

Outcome Measures

Primary Outcomes (1)

• The incidence of postoperative residual curarization

  The incidence of elderly patients that Train of Four(TOF) rate \<0.9 in the postoperative care unit

  through study completion( anticipated 5 months)

Interventions

Train of four monitoring DEVICE

Train of four monitoring in postoperative care unit

Eligibility Criteria

• Age: 65 Years - 95 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Electively operated elderly patients \>65 years old under general anesthesia

You may qualify if:

• age \>65
• general anesthesia using non-depolarizing neuromuscular blocker

You may not qualify if:

• Patients with an ASA score greater than 3
• Those with contraindications to anesthetic drugs
• Those with neuromuscular, neurological and psychiatric diseases
• Patients in whom TOF monitoring is not possible in the ulnar nerve region
• Patients with advanced renal failure
• Patients with advanced hepatic insufficiency
• Those with decompensated heart failure
• Patients with BMI\<18 and BMI\>30
• Patients with uncontrolled hypertension, uncontrolled diabetes, pheochromocytoma, thyroid dysfunction
• Those who are incapable of reading and signing the consent form
• Patients who do not want to sign the consent form
• Patients deemed unsuitable by the investigator
• Those with chronic opioid use

Sponsors & Collaborators

• Ankara City Hospital Bilkent: lead

Study Sites (1)

Ankara City Hospital

Ankara, 06800, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Delayed Emergence from Anesthesia

Interventions

Neuromuscular Monitoring

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Monitoring, Physiologic; Diagnostic Techniques and Procedures; Diagnosis

Study Officials

• Aysun Postaci

  Ankara City Hospital Bilkent

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Aysun Postaci

CONTACT

+90 5323520383; aysunposta@yahoo.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Ass. Prof. Dr. Nadide Aysun Postaci

Study Record Dates

• First Submitted: August 2, 2021
• First Posted: September 21, 2021
• Study Start: August 15, 2021
• Primary Completion: December 1, 2021
• Study Completion: December 1, 2021
• Last Updated: September 21, 2021

Record last verified: 2021-09

Locations

TU (1)