NCT05044260

Brief Summary

Various attempts have been implemented using different materials and techniques to augment the maxillary sinus floor enhancing autogenous bone formation to allow proper dental implant positioning. The aim of this study is to evaluate the sinus lift procedure using polytetrafluoroethylene (PTFE) titanium-reinforced membrane to maintain the space formed after Schneiderian membrane elevation followed by immediate implant placement.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
12

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Sep 2020

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2020

Completed
1 year until next milestone

First Submitted

Initial submission to the registry

September 6, 2021

Completed
8 days until next milestone

First Posted

Study publicly available on registry

September 14, 2021

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 20, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 20, 2021

Completed
Last Updated

September 14, 2021

Status Verified

September 1, 2021

Enrollment Period

1.1 years

First QC Date

September 6, 2021

Last Update Submit

September 6, 2021

Conditions

Outcome Measures

Primary Outcomes (4)

  • Change in implant stability

    It will be measured using Osstell

    at baseline and 6 months

  • Change in bone formation

    It will be measured uisng CBCT on Demand 3d software

    at baseline and 6 months

  • Change in bone height

    It will be measured uisng CBCT on Demand 3d software

    at baseline and 6 months

  • Change in bone density

    It will be measured uisng CBCT on Demand 3d software

    at baseline and 6 months

Study Arms (1)

Direct Sinus elevation using SLA Kit

EXPERIMENTAL
Procedure: Direct sinus lift with titanium reinforced PTFE membrane

Interventions

Implants will be placed immediately after sinus lifting procedure and maintaining the sinus membrane in position using PTFE titanium reinforced membrane.

Direct Sinus elevation using SLA Kit

Eligibility Criteria

Age40 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Patients of both genders requiring implant placement in posterior maxilla
  • Age range: 40-60 years.
  • Good oral hygiene
  • Healthy maxillary sinus free from pathology
  • The minimum crestal bone height is (4-6) mm
  • Patients who are willing and fully capable to comply with the study protocol.

You may not qualify if:

  • Sinus infection
  • Tumors or pathologic lesions in sinus
  • Severe allergic rhinitis.
  • Chronic topical steroid use.
  • Radiation therapy.
  • Psychologic / mental impairment
  • Acute infection (periodontitis or mucosal infection
  • Patients on radiotherapy or chemotherapy.
  • Alcohol or drug abuse.
  • Patient with systemic disorder (uncontrolled Diabetes mellitus, autoimmune diseases, bone diseases, etc.)
  • Smokers
  • Parafuctional habits

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Alexandria Faculty of Dentistry

Alexandria, Egypt

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Assistant lecturer of DPH and Clinical statistician

Study Record Dates

First Submitted

September 6, 2021

First Posted

September 14, 2021

Study Start

September 1, 2020

Primary Completion

October 20, 2021

Study Completion

October 20, 2021

Last Updated

September 14, 2021

Record last verified: 2021-09

Locations